{"id":"W2096904352","doi":"10.1186/scrt460","title":"Low-dose insulin-like growth factor binding proteins 1 and 2 and angiopoietin-like protein 3 coordinately stimulate ex vivo expansion of human umbilical cord blood hematopoietic stem cells as assayed in NOD/SCID gamma null mice","year":2014,"lang":"en","type":"article","venue":"Stem Cell Research & Therapy","topic":"Hematopoietic Stem Cell Transplantation","field":"Medicine","cited_by":22,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Medical Research Council","keywords":"Ex vivo; Stem cell; Haematopoiesis; Cell biology; Umbilical cord; Biology; Stem cell factor; Growth factor; Cord blood; Hematopoietic growth factor; Hematopoietic stem cell; Insulin; In vivo; Immunology; Endocrinology; Biochemistry; Receptor","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.003148122,0.0006056501,0.001168731,0.0008620881,0.0002833141,0.000127488,0.0003840003,0.0004857683,0.0001456421],"category_scores_gemma":[0.00003707426,0.0005375133,0.0001590398,0.0009516709,0.0005601736,0.000225794,0.0001580292,0.001028197,0.00005100006],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001738501,"about_ca_system_score_gemma":0.0003588586,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0005646572,"about_ca_topic_score_gemma":0.00004137656,"domain_scores_codex":[0.9931878,0.001472746,0.001190419,0.001241586,0.001730712,0.001176668],"domain_scores_gemma":[0.9967236,0.0009667708,0.0003204669,0.0007749108,0.0005520153,0.0006622558],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002655625,0.0009373642,0.002681929,0.003362743,0.0000845352,0.0002069271,0.0057588,0.000001665342,0.9813204,0.0001268461,0.00002511368,0.00283804],"study_design_scores_gemma":[0.01253656,0.005347086,0.002708733,0.00208387,0.00004977449,0.0001127807,0.001467672,0.0003084912,0.974546,0.0001913349,0.000142761,0.0005050024],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.991658,0.000765141,0.0001229697,0.0002230855,0.00009379022,0.006378509,0.00003503915,0.0001007092,0.0006227895],"genre_scores_gemma":[0.996484,0.0006309082,0.0003752041,0.0000558096,0.0000649236,0.0002707304,0.00002198215,0.0001535999,0.001942779],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009880933,"threshold_uncertainty_score":0.9997076,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04209908609413798,"score_gpt":0.3170214470824292,"score_spread":0.2749223609882912,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}