{"id":"W2097007448","doi":"10.3899/jrheum.100069","title":"Responses to Adalimumab in Patients with Active Psoriatic Arthritis Who Have Not Adequately Responded to Prior Therapy: Effectiveness and Safety Results From an Open-label Study","year":2010,"lang":"en","type":"article","venue":"The Journal of Rheumatology","topic":"Spondyloarthritis Studies and Treatments","field":"Medicine","cited_by":67,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Université de Montréal; Université Laval; Abbott (Canada); Toronto Western Hospital; University of Toronto","funders":"Abbott Laboratories","keywords":"Medicine; Adalimumab; Dactylitis; Psoriatic arthritis; Internal medicine; Psoriasis Area and Severity Index; Psoriasis; Adverse effect; Enthesitis; Rheumatology; Arthritis; Physical therapy; Dermatology; Rheumatoid arthritis","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.003274719,0.0005709559,0.002072245,0.0002923891,0.0003563572,0.0006189882,0.0003910844,0.001164058,0.001373774],"category_scores_gemma":[0.002967314,0.0002885773,0.001131481,0.0002855629,0.0004236895,0.0007206753,0.0001923359,0.001040953,0.0003450983],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003341996,"about_ca_system_score_gemma":0.0003095203,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001743996,"about_ca_topic_score_gemma":0.0002647379,"domain_scores_codex":[0.9986258,0.0006700748,0.0001808871,0.0001666518,0.0002702035,0.00008643125],"domain_scores_gemma":[0.9968923,0.001429882,0.0008380271,0.0002070948,0.000187237,0.0004454482],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.5938193,0.04536244,0.1396195,0.002493568,0.003652923,0.0008348879,0.000534423,0.001251602,0.03265277,0.00009313169,0.001259998,0.1784255],"study_design_scores_gemma":[0.1901098,0.5388425,0.2547521,0.0001870437,0.002151245,0.002393783,0.0001792553,0.003244916,0.004997529,0.00009521539,0.002961887,0.000084733],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9966152,0.002610176,0.0001776101,0.00004646409,0.00002776923,0.0001455878,0.00009828815,0.00001376034,0.0002651205],"genre_scores_gemma":[0.9978408,0.0006889031,0.0003995388,0.0002401332,0.0001522673,0.0001717995,0.0003045793,0.000004394444,0.0001976908],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003274719,"threshold_uncertainty_score":0.01731861,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02256382361503234,"score_gpt":0.3148059316831873,"score_spread":0.2922421080681549,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}