{"id":"W2097014087","doi":"10.1016/j.bbmt.2012.11.186","title":"Safety and Efficacy From Intravenous Busulfan with PK-Directed Dosed Adjustment and Bortezomib Conditioning Regimen in Relapsed Multiple Myeloma Patients Undergoing a Second Autologous Hematopoietic Stem Cell Transplantation","year":2013,"lang":"en","type":"article","venue":"Biology of Blood and Marrow Transplantation","topic":"Multiple Myeloma Research and Treatments","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"Queen Elizabeth II Health Sciences Centre; Princess Margaret Cancer Centre; Dalhousie University","funders":"","keywords":"Medicine; Multiple myeloma; Busulfan; Bortezomib; Regimen; Hematopoietic stem cell transplantation; Transplantation; Surgery; Urology; Pharmacokinetics; Progressive disease; Dosing; Autologous stem-cell transplantation; Internal medicine; Chemotherapy","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009087551,0.0003698132,0.0008031647,0.0001793393,0.0002375732,0.0004544432,0.0002693032,0.0003462369,0.0005073674],"category_scores_gemma":[0.001055463,0.000191145,0.0004517887,0.0001838736,0.000316791,0.0002963744,0.0001743796,0.0008665143,0.0001550331],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003964043,"about_ca_system_score_gemma":0.0007037327,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003955111,"about_ca_topic_score_gemma":0.0008200927,"domain_scores_codex":[0.9995652,0.0002193644,0.00003165834,0.00005481282,0.00007867299,0.00005033813],"domain_scores_gemma":[0.9994653,0.00008933755,0.0001922049,0.00004463759,0.0000237705,0.0001847345],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"randomized_trial","study_design_gemma":"nonrandomized_trial","study_design_scores_codex":[0.3140063,0.02473223,0.310755,0.0002939828,0.001116897,0.0005978353,0.0004672564,0.003116352,0.0791873,0.0002054253,0.001188422,0.264333],"study_design_scores_gemma":[0.03624273,0.6073578,0.3321288,0.00006018627,0.0006278653,0.001744083,0.000143047,0.003707122,0.01495295,0.0001402405,0.002860297,0.00003481461],"study_design_candidate":"nonrandomized_trial","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9991184,0.0005330051,0.0000822747,0.00002734987,0.000009484152,0.00004874475,0.0000310853,0.000007116219,0.0001425053],"genre_scores_gemma":[0.9991666,0.0001851092,0.0002027489,0.00008107648,0.00002946789,0.00005966187,0.000160918,0.000002166336,0.0001122963],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0009087551,"threshold_uncertainty_score":0.004806042,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007199685666502442,"score_gpt":0.2159424497131635,"score_spread":0.2087427640466611,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}