{"id":"W2097092564","doi":"10.1089/hum.2005.16.1276","title":"Gene Therapy for Lipoprotein Lipase Deficiency: Working Toward Clinical Application","year":2005,"lang":"en","type":"article","venue":"Human Gene Therapy","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":62,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"","keywords":"Lipoprotein lipase; Hypertriglyceridemia; Pancreatitis; Medicine; Internal medicine; Endocrinology; Pathology; Biology; Triglyceride; Adipose tissue; Cholesterol","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001331903,0.0003467858,0.0003221086,0.0001015051,0.0003463061,0.00007510838,0.0007063666,0.0003189897,0.0001013222],"category_scores_gemma":[0.00002279843,0.0003242324,0.000344005,0.0001741049,0.000180764,0.000008118973,0.00007450611,0.0002126196,0.00005485313],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000465171,"about_ca_system_score_gemma":0.0001722624,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001850219,"about_ca_topic_score_gemma":0.0001075071,"domain_scores_codex":[0.9973286,0.0002219088,0.0005868244,0.0008938252,0.0003251492,0.0006437039],"domain_scores_gemma":[0.998353,0.00003535282,0.0001958609,0.001049625,0.0001776532,0.0001884914],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002813533,0.0003225998,0.0002715827,0.00000361811,0.00007012398,7.163395e-7,0.00007656334,0.00007290323,0.677735,0.00003914969,0.0004776224,0.3181165],"study_design_scores_gemma":[0.003764368,0.00583039,0.0007773198,0.000005302169,0.00000695168,0.000006729656,0.00001583961,0.0001955285,0.8917796,0.0004220112,0.09677983,0.0004161235],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9770978,0.01185646,0.008244184,0.0006013612,0.0001060595,0.001758256,0.00001900963,0.00007113871,0.0002457012],"genre_scores_gemma":[0.9836103,0.005909471,0.00377609,0.001866112,0.003065003,0.0008082723,0.000301589,0.0001212778,0.0005418401],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3177004,"threshold_uncertainty_score":0.999921,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08667525330993776,"score_gpt":0.3865112433727948,"score_spread":0.299835990062857,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}