{"id":"W2097098083","doi":"10.1261/rna.31506","title":"Probing the structure and function of an archaeal C/D-box methylation guide sRNA","year":2006,"lang":"en","type":"article","venue":"RNA","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":28,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"National Science Foundation","keywords":"Biology; Sulfolobus solfataricus; Methylation; Transfer RNA; Guide RNA; RNA; Small nucleolar RNA; Pseudouridine; Ribosomal RNA; Ribonucleoprotein; RNA methylation; Nucleic acid structure; Non-coding RNA; Genetics; Methyltransferase; Archaea; DNA; Genome; Gene; Cas9","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001304771,0.000199573,0.0001296396,0.0001042571,0.0001753059,0.0001753169,0.000177698,0.0003389035,0.0004325639],"category_scores_gemma":[0.0002475461,0.000122648,0.0001302482,0.00007630209,0.0001649493,0.0001020073,0.0001025041,0.0002280257,0.0002228245],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003223206,"about_ca_system_score_gemma":0.0002114347,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002110903,"about_ca_topic_score_gemma":0.002285349,"domain_scores_codex":[0.9999074,0.00001874711,0.000006357576,0.00002432102,0.00002924624,0.00001407845],"domain_scores_gemma":[0.9998808,0.00003423246,0.00002902928,0.00001429222,0.00001559417,0.00002598696],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004978658,0.00001122604,0.001016768,0.00001659419,0.000003013243,0.00002460777,0.00001357237,0.0001352402,0.9981178,0.00005269606,0.000004849408,0.0005539772],"study_design_scores_gemma":[0.000006660055,0.000190649,0.008812473,0.000003127059,0.000007074584,0.0001122255,0.00003433566,0.002209951,0.9879079,0.00004082829,0.000669805,0.00000484686],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9986853,0.0002062432,0.0008082162,0.00001686509,0.000002035699,0.000005084972,0.00004344514,0.00001251444,0.0002202092],"genre_scores_gemma":[0.9976439,0.0001068886,0.001777871,0.00001566161,0.000001239492,0.000004424448,0.0001090211,0.000005213926,0.0003358147],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002110903,"threshold_uncertainty_score":0.00419724,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007256407447813748,"score_gpt":0.2271781462975811,"score_spread":0.2199217388497674,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}