{"id":"W2097141045","doi":"10.1172/jci71090","title":"Heparan sulfate deficiency disrupts developmental angiogenesis and causes congenital diaphragmatic hernia","year":2013,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Congenital Diaphragmatic Hernia Studies","field":"Medicine","cited_by":68,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Eunice Kennedy Shriver National Institute of Child Health and Human Development; National Center for Research Resources; National Institute of General Medical Sciences; National Heart, Lung, and Blood Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"Heparan sulfate; Biology; Congenital diaphragmatic hernia; Perlecan; Cell biology; Angiogenesis; Knockout mouse; Cancer research; Immunology; Internal medicine; Receptor; Genetics; Biochemistry; Medicine; Heparin","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009902214,0.0002000156,0.0007274273,0.0001577817,0.00009852618,0.00006510591,0.00009715933,0.0001299356,0.0001422826],"category_scores_gemma":[0.003718615,0.0001482684,0.000227661,0.0002202956,0.0004297498,0.0004019472,0.00006400901,0.0002676485,0.0001286709],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005463186,"about_ca_system_score_gemma":0.0002902816,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00005631894,"about_ca_topic_score_gemma":0.00004958549,"domain_scores_codex":[0.9970731,0.0001780258,0.001820022,0.0001943445,0.0004999846,0.0002345177],"domain_scores_gemma":[0.9973781,0.0008205347,0.0006813961,0.0001254535,0.0004821723,0.0005123898],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.00008769914,0.0001948105,0.9617397,0.0001494623,0.0003926285,0.00006838544,0.0008935127,0.000001855121,0.006004219,0.00008020111,0.001313804,0.02907371],"study_design_scores_gemma":[0.001662309,0.0004367251,0.9936385,0.0001833895,0.0003607691,0.0004319507,0.0005718509,0.0002423844,0.0007702188,0.001245561,0.0002906508,0.0001656575],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9953412,0.001360184,0.00005502891,0.001972039,0.0002794605,0.0003811182,0.000005025123,0.00002239662,0.0005835571],"genre_scores_gemma":[0.992964,0.0003330304,0.005619501,0.0006444784,0.0002272225,0.00001319885,0.00000483482,0.00002186666,0.0001718987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03189882,"threshold_uncertainty_score":0.604621,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06549491272047092,"score_gpt":0.3483720094520007,"score_spread":0.2828770967315298,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}