{"id":"W2097275308","doi":"10.1093/molehr/gar005","title":"Wide-ranging DNA methylation differences of primary trophoblast cell populations and derived cell lines: implications and opportunities for understanding trophoblast function†","year":2011,"lang":"en","type":"article","venue":"Molecular Human Reproduction","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Queen's University; Wellcome Trust; Yale University","keywords":"DNA methylation; Biology; Trophoblast; Epigenetics; Methylation; Genetics; Gene; Cell biology; Gene expression; Placenta; Fetus","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002240617,0.000158762,0.0001696414,0.0001391843,0.0002745008,0.000027486,0.00005517631,0.0001077738,0.000004199085],"category_scores_gemma":[0.00003818529,0.0001705583,0.00006588083,0.00007547019,0.0001192963,0.00001541515,0.00004692674,0.0000519784,1.343365e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002499707,"about_ca_system_score_gemma":0.00003142249,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000227182,"about_ca_topic_score_gemma":0.00001982636,"domain_scores_codex":[0.9988866,0.00007150089,0.0003231649,0.0004805277,0.00009231751,0.0001458646],"domain_scores_gemma":[0.9992166,0.00001439807,0.0002388299,0.0003240888,0.0001487569,0.00005739869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005264404,0.0000603567,0.002633035,0.00009502682,0.00002301134,1.961029e-7,0.0002194312,0.00005953072,0.994118,0.001188182,0.00001068223,0.001539886],"study_design_scores_gemma":[0.0005776262,0.0005494988,0.06907231,0.00001739905,0.0001458288,0.000002268184,0.0007041716,0.00005961031,0.9167825,0.01166287,0.0001822413,0.0002436612],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.7611417,0.001635765,0.2362935,0.00006380902,0.00008189931,0.0003114457,0.00001237259,0.00001363966,0.0004459602],"genre_scores_gemma":[0.9957699,0.0004243281,0.003233193,0.00002236579,0.00008250304,0.00005269246,0.0002382207,0.00002900747,0.0001477661],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.2346283,"threshold_uncertainty_score":0.6955164,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.125075948900514,"score_gpt":0.261505154437739,"score_spread":0.1364292055372251,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}