{"id":"W2097292329","doi":"10.1021/bp0101029","title":"Metabolic Flux Variation of Saccharomyces cerevisiae Cultivated in a Multistage Continuous Stirred Tank Reactor Fermentation Environment","year":2001,"lang":"en","type":"article","venue":"Biotechnology Progress","topic":"Microbial Metabolic Engineering and Bioproduction","field":"Biochemistry, Genetics and Molecular Biology","cited_by":17,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"","keywords":"Industrial fermentation; Fermentation; Pyruvate decarboxylase; Pentose phosphate pathway; Biochemistry; Pyruvate carboxylase; Chemistry; Flux (metallurgy); Citric acid cycle; Metabolic flux analysis; Glycolysis; Ethanol fermentation; Saccharomyces cerevisiae; Metabolism; Biology; Ethanol; Yeast; Enzyme; Alcohol dehydrogenase; Organic chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002283425,0.0004455271,0.0004861036,0.0002816562,0.0001497638,0.0004715669,0.000183274,0.0002542131,0.0001911123],"category_scores_gemma":[0.0002775135,0.0001257798,0.0002794405,0.000452431,0.0001634798,0.0002255641,0.0001578083,0.0003135582,0.00005963529],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003996018,"about_ca_system_score_gemma":0.0001790302,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001719502,"about_ca_topic_score_gemma":0.001076081,"domain_scores_codex":[0.9998327,0.00003449179,0.00001473401,0.00005581073,0.0000402468,0.0000218784],"domain_scores_gemma":[0.9998379,0.00005687838,0.00002599288,0.00001519791,0.0000407672,0.00002326811],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002517814,0.00002277478,0.00126049,0.00001379736,0.000007014734,0.00002588448,0.00001665948,0.0004497431,0.9967578,0.00003540837,0.000007801924,0.001150883],"study_design_scores_gemma":[0.00001647609,0.0003498344,0.01793235,0.000003356797,0.00003020394,0.00006078307,0.00004826143,0.01331699,0.9677954,0.00006456935,0.0003655767,0.0000161542],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9980409,0.00007397404,0.001517465,0.000009726008,0.000003983818,0.000004702737,0.0002191688,0.0000211192,0.0001089283],"genre_scores_gemma":[0.9957118,0.0001632401,0.003289416,0.000008956414,0.000002540118,0.00001450745,0.0005547409,0.00001284901,0.0002420817],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001719502,"threshold_uncertainty_score":0.003418922,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006654715903735506,"score_gpt":0.2264568156442239,"score_spread":0.2198020997404884,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}