{"id":"W2097303935","doi":"10.2967/jnumed.110.076356","title":"Biodistribution and Uptake of 3′-Deoxy-3′-Fluorothymidine in ENT1-Knockout Mice and in an ENT1-Knockdown Tumor Model","year":2010,"lang":"en","type":"article","venue":"Journal of Nuclear Medicine","topic":"Adenosine and Purinergic Signaling","field":"Biochemistry, Genetics and Molecular Biology","cited_by":54,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Alberta","funders":"Canadian Cancer Society Research Institute; Canadian Institutes of Health Research; Alberta Heritage Foundation for Medical Research; Fondation pour la Recherche Médicale; Cancer Research Institute","keywords":"Biodistribution; Molecular biology; Chemistry; Thymidine kinase; Transfection; Biology; Biochemistry; Gene; In vitro; Virology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003620059,0.0007409478,0.0003993452,0.0008069286,0.0002779674,0.0004463064,0.0004220357,0.0008493707,0.001760898],"category_scores_gemma":[0.0001179905,0.0004105541,0.0004343391,0.0002936658,0.0005741863,0.0005042066,0.000175983,0.0008926952,0.0006898853],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0007087167,"about_ca_system_score_gemma":0.0002297134,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001054168,"about_ca_topic_score_gemma":0.001594402,"domain_scores_codex":[0.9997317,0.0000271201,0.00002515283,0.00009996095,0.00005453993,0.00006148944],"domain_scores_gemma":[0.9996941,0.00003965805,0.0001312805,0.0000258467,0.00002647652,0.0000826153],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002528065,0.00005825934,0.0002436785,0.00002232075,0.000007532675,0.00007668688,0.00002197615,0.0000526106,0.9986416,0.00007223204,0.0000452393,0.0005050341],"study_design_scores_gemma":[0.00007134141,0.001075079,0.007270293,0.00001037119,0.00006958599,0.00108064,0.00006515147,0.001264569,0.9868881,0.00005411146,0.002136686,0.00001413307],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9920802,0.001285007,0.003807983,0.000154402,0.00003575785,0.00004890027,0.001443946,0.0001783293,0.0009656678],"genre_scores_gemma":[0.9803724,0.001742571,0.005850964,0.0001135184,0.0000190782,0.0001536681,0.002395362,0.0001591451,0.009193409],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001760898,"threshold_uncertainty_score":0.005890787,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009892244103685392,"score_gpt":0.2574771559399112,"score_spread":0.2475849118362258,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}