{"id":"W2097321304","doi":"10.1095/biolreprod.106.051557","title":"Dynamic HIF1A Regulation During Human Placental Development1","year":2006,"lang":"en","type":"article","venue":"Biology of Reproduction","topic":"Cancer, Hypoxia, and Metabolism","field":"Biochemistry, Genetics and Molecular Biology","cited_by":129,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hospital for Sick Children; SickKids Foundation; Mount Sinai Hospital; University of Toronto","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"HIF1A; Biology; Oxygen tension; Syncytiotrophoblasts; Placentation; Cell biology; Hypoxia-inducible factors; Placenta; Endocrinology; Internal medicine; Cancer research; Biochemistry; Angiogenesis; Genetics; Fetus; Chemistry; Oxygen; Gene; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001370971,0.00009436257,0.0001129578,0.00005592157,0.00008732358,0.000003255445,0.0000613444,0.000127311,0.00001796882],"category_scores_gemma":[0.00002052943,0.00009765941,0.00004993211,0.00006109352,0.0001014405,0.000004121668,0.00003783091,0.00004043195,0.000003583946],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002404588,"about_ca_system_score_gemma":0.00002721897,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00008958053,"about_ca_topic_score_gemma":0.00008529019,"domain_scores_codex":[0.9991636,0.00003400111,0.0002068456,0.0004087911,0.00004748922,0.0001393272],"domain_scores_gemma":[0.9995188,0.00000109901,0.0001291525,0.0002756943,0.0000586321,0.00001669275],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00005538438,0.00003489295,0.003658585,0.00001086488,0.0000171106,4.694693e-8,0.00001264339,0.00006318881,0.9915169,0.0001948342,0.000535753,0.003899801],"study_design_scores_gemma":[0.0004126854,0.0000552699,0.2402157,0.000004390689,0.000009390652,0.00002737936,0.00001564215,0.000003815188,0.680494,0.0002622831,0.07838847,0.0001109582],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9935315,0.004386101,0.0002759047,0.0000708122,0.001117007,0.0001254825,0.000007436009,0.00001874632,0.0004670333],"genre_scores_gemma":[0.9943454,0.0002581077,0.0009404484,0.000004442086,0.001178498,0.000008968295,0.0005384789,0.00001110192,0.002714609],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3110229,"threshold_uncertainty_score":0.3982435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005473230789346117,"score_gpt":0.2360881209991249,"score_spread":0.2306148902097788,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}