{"id":"W2097336654","doi":"10.1089/ten.2006.12.2639","title":"Suppression of Genes Related to Hypertrophy and Osteogenesis in Committed Human Mesenchymal Stem Cells Cultured on Novel Nitrogen-Rich Plasma Polymer Coatings","year":2006,"lang":"en","type":"article","venue":"Tissue Engineering","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":88,"is_retracted":false,"has_abstract":true,"ca_institutions":"Hôpital Notre-Dame; Polytechnique Montréal; McGill University; Jewish General Hospital","funders":"Natural Sciences and Engineering Research Council of Canada","keywords":"Endochondral ossification; Mesenchymal stem cell; Cell biology; Osteocalcin; Cartilage; Chemistry; Aggrecan; Chondrocyte; Alkaline phosphatase; Anatomy; Pathology; Biology; Osteoarthritis; Medicine; Biochemistry","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001191987,0.0002346176,0.0001290144,0.00008893545,0.00006358425,0.0001295722,0.0001269114,0.0001323595,0.0004791211],"category_scores_gemma":[0.0001392603,0.00009342437,0.0001230312,0.00006474472,0.0001730834,0.0001160067,0.0001363968,0.0001443556,0.0001080571],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00008510521,"about_ca_system_score_gemma":0.0000900826,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002595984,"about_ca_topic_score_gemma":0.0004348147,"domain_scores_codex":[0.9999106,0.00001391146,0.000007754667,0.00001670299,0.00003970672,0.00001138849],"domain_scores_gemma":[0.9998944,0.00003869875,0.00002875392,0.0000124043,0.00001295533,0.00001284511],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00001684499,0.000002878954,0.00003361528,0.000007802728,5.807242e-7,0.00001385725,0.00000443559,0.00001610057,0.999607,0.00000998702,0.000001902832,0.0002850454],"study_design_scores_gemma":[0.000002758197,0.00007304557,0.001028371,0.000001137512,0.000002853249,0.00006335357,0.000005220722,0.0002606507,0.9982558,0.000008652353,0.0002972994,8.454723e-7],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959379,0.0005645862,0.002484719,0.00001671723,0.000008274274,0.00001517453,0.0000521679,0.00001768572,0.000902624],"genre_scores_gemma":[0.9940068,0.0005538707,0.003374434,0.00002488389,0.000005958621,0.00002439298,0.0001375722,0.00001419335,0.001857975],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004791211,"threshold_uncertainty_score":0.001602829,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008027737998249919,"score_gpt":0.2200662630920542,"score_spread":0.2120385250938043,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}