{"id":"W2097377148","doi":"10.1182/asheducation-2011.1.143","title":"How I Diagnose and Manage HIT","year":2011,"lang":"en","type":"review","venue":"Hematology","topic":"Heparin-Induced Thrombocytopenia and Thrombosis","field":"Medicine","cited_by":157,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Heparin-induced thrombocytopenia; Argatroban; Lepirudin; Fondaparinux; Medicine; Platelet factor 4; Antithrombin; Heparin; Discovery and development of direct thrombin inhibitors; Dosing; Partial thromboplastin time; Direct thrombin inhibitor; Platelet activation; Intensive care medicine; Thrombosis; Platelet; Pharmacology; Immunology; Internal medicine; Thrombin; Dabigatran; Warfarin; Venous thromboembolism","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002326947,0.001127664,0.001219268,0.002305069,0.001811655,0.004615961,0.002396038,0.006123855,0.0163345],"category_scores_gemma":[0.0185404,0.0005121451,0.001157884,0.0008779119,0.001893958,0.006033963,0.002916966,0.01121604,0.01558924],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00220436,"about_ca_system_score_gemma":0.005015043,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004159591,"about_ca_topic_score_gemma":0.005043643,"domain_scores_codex":[0.9977477,0.0006328354,0.0002992773,0.0003293938,0.0006050355,0.0003857653],"domain_scores_gemma":[0.9942416,0.001107302,0.0005400697,0.0002560359,0.001841928,0.00201298],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007950478,0.0002541842,0.007676766,0.000857208,0.00007193777,0.003063089,0.0005441146,0.0003817621,0.0004945265,0.004564378,0.7085803,0.2734322],"study_design_scores_gemma":[0.0001745987,0.0004159315,0.007853633,0.0108186,0.0002046345,0.02992176,0.003267548,0.00139051,0.000891097,0.05057839,0.8942701,0.0002131546],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"commentary","genre_gemma":"review","genre_scores_codex":[0.005986806,0.08872448,0.02410893,0.762056,0.0398361,0.0007324378,0.0006753479,0.002145918,0.07573392],"genre_scores_gemma":[0.08525259,0.2150661,0.06780215,0.4952415,0.08971632,0.001378913,0.00234511,0.000919675,0.04227775],"genre_candidate":"review","genre_consensus":null,"teacher_disagreement_score":0.0163345,"threshold_uncertainty_score":0.05464435,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1278396842040911,"score_gpt":0.3559724876094751,"score_spread":0.228132803405384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}