{"id":"W2097377148","doi":"10.1182/asheducation-2011.1.143","title":"How I Diagnose and Manage HIT","year":2011,"lang":"en","type":"review","venue":"Hematology","topic":"Heparin-Induced Thrombocytopenia and Thrombosis","field":"Medicine","cited_by":157,"is_retracted":false,"has_abstract":true,"ca_institutions":"McMaster University","funders":"","keywords":"Heparin-induced thrombocytopenia; Argatroban; Lepirudin; Fondaparinux; Medicine; Platelet factor 4; Antithrombin; Heparin; Discovery and development of direct thrombin inhibitors; Dosing; Partial thromboplastin time; Direct thrombin inhibitor; Platelet activation; Intensive care medicine; Thrombosis; Platelet; Pharmacology; Immunology; Internal medicine; Thrombin; Dabigatran; Warfarin; Venous thromboembolism","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001177332,0.0004802486,0.00375531,0.0002709412,0.00006315857,0.00002859567,0.0001719869,0.0007757086,0.0002793652],"category_scores_gemma":[0.000144127,0.0003649612,0.0003407446,0.0001947283,0.000182124,0.00006081342,0.000217708,0.0005345116,0.0004577611],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004857503,"about_ca_system_score_gemma":0.0001266145,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002598468,"about_ca_topic_score_gemma":0.00001892836,"domain_scores_codex":[0.9983051,0.0001303928,0.0004119515,0.0006119352,0.00008852906,0.0004520334],"domain_scores_gemma":[0.9985853,0.0001980175,0.0002309429,0.0006790131,0.00003596523,0.0002707069],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00000619395,0.0001529056,0.0002108016,0.03955761,0.0007262924,0.001074682,0.0001026539,1.075056e-10,7.623801e-7,0.04656452,0.002955155,0.9086484],"study_design_scores_gemma":[0.0003469741,0.0001083041,0.00008718431,0.005531799,0.00219624,0.005172444,0.00001797039,1.342012e-7,0.000007802685,0.0002432656,0.9859802,0.0003076603],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0001349259,0.9859288,0.000009713664,0.0002988194,0.0002899586,0.0009159332,0.00001020061,0.0001000459,0.01231164],"genre_scores_gemma":[0.0004030847,0.9965002,0.0003102645,0.0001387756,0.0001136446,0.0001864154,0.00006156157,0.00009000375,0.002196077],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9830251,"threshold_uncertainty_score":0.9998803,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1278396842040911,"score_gpt":0.3559724876094751,"score_spread":0.228132803405384,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}