{"id":"W2097448914","doi":"10.1172/jci25509","title":"Cannabinoids promote embryonic and adult hippocampus neurogenesis and produce anxiolytic- and antidepressant-like effects","year":2005,"lang":"en","type":"article","venue":"Journal of Clinical Investigation","topic":"Cannabis and Cannabinoid Research","field":"Medicine","cited_by":527,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan","funders":"Canadian Institutes of Health Research; Saskatchewan Health Research Foundation; Heart and Stroke Foundation of Canada","keywords":"Neurogenesis; Dentate gyrus; Hippocampal formation; Neuroscience; Cannabinoid receptor; Anxiolytic; Neural stem cell; Hippocampus; Cannabinoid; Pharmacology; Biology; Medicine; Stem cell; Internal medicine; Receptor; Cell biology; Agonist","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00169732,0.0001799564,0.0006089873,0.0001610719,0.00009823841,0.00007924131,0.00007378608,0.0001831603,0.00000541532],"category_scores_gemma":[0.003337937,0.0001359157,0.0001048357,0.0001787799,0.0005344413,0.0002841833,0.0000755124,0.0006366429,0.000001673116],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002827681,"about_ca_system_score_gemma":0.0003798979,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00002069525,"about_ca_topic_score_gemma":0.00001594866,"domain_scores_codex":[0.9977404,0.0002636476,0.0009208405,0.0003454852,0.0004704903,0.000259129],"domain_scores_gemma":[0.997891,0.0001161528,0.0004614426,0.0002043576,0.0005594048,0.0007676484],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.0009024871,0.0002809814,0.517301,0.001067573,0.0001897744,0.0001724572,0.0003692497,0.000008537178,0.03549829,0.0001402813,0.02669708,0.4173723],"study_design_scores_gemma":[0.003994881,0.002511171,0.9675916,0.0004229951,0.0003048203,0.001353685,0.00003744734,0.001904069,0.01157308,0.0008887992,0.009234105,0.0001832934],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9468214,0.003244893,0.00001409432,0.04925258,0.0001915563,0.0004278245,0.000001826465,0.00001405638,0.00003179792],"genre_scores_gemma":[0.9917744,0.003002963,0.001207789,0.002268726,0.0009216786,0.000008068687,0.000002453187,0.00002727294,0.0007866095],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.4502907,"threshold_uncertainty_score":0.5542483,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02596151156862688,"score_gpt":0.3436696183526028,"score_spread":0.3177081067839759,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}