{"id":"W2097463362","doi":"10.1101/gad.1310805","title":"RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis","year":2005,"lang":"en","type":"article","venue":"Genes & Development","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":292,"is_retracted":false,"has_abstract":true,"ca_institutions":"Ontario Institute for Cancer Research","funders":"McGill University; Amgen","keywords":"RhoC; Biology; Cell biology; Stress fiber; Metastasis; Motility; Cell adhesion; Cancer research; Focal adhesion; Cell; Signal transduction; Cancer; RHOA; Genetics","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001628171,0.0005169225,0.0002797662,0.000582004,0.0003043895,0.0004090033,0.0004056302,0.0004210086,0.002006887],"category_scores_gemma":[0.0002202688,0.00032395,0.0002285041,0.000218914,0.0004196265,0.0001931366,0.0004298038,0.0006637641,0.001158381],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003356805,"about_ca_system_score_gemma":0.0004913866,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007947232,"about_ca_topic_score_gemma":0.001309189,"domain_scores_codex":[0.9997512,0.00003558496,0.00002315942,0.00004961668,0.00009843442,0.00004207284],"domain_scores_gemma":[0.999446,0.0001059093,0.0001836897,0.00007878275,0.00004346874,0.0001421578],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007120753,0.00001173864,0.0002608713,0.00002705624,0.000002715078,0.0002265717,0.000006753921,0.00006025367,0.9976097,0.0003263925,0.00005398395,0.001342653],"study_design_scores_gemma":[0.00003408191,0.0001615964,0.01789932,0.00002519694,0.00002548832,0.002720723,0.00002971409,0.001287733,0.9663824,0.0002545478,0.01116421,0.00001492494],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9823471,0.004073018,0.00484806,0.0002809417,0.00003570531,0.0000288133,0.001678073,0.0003709768,0.006337191],"genre_scores_gemma":[0.9888021,0.001463119,0.002205322,0.00005430318,0.0000176798,0.00003077736,0.001676299,0.0001177075,0.005632737],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002006887,"threshold_uncertainty_score":0.006713688,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01539486329926219,"score_gpt":0.2624939073504111,"score_spread":0.2470990440511489,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}