{"id":"W2097499299","doi":"10.1093/neuonc/nov061.81","title":"MB-05 * PHARMACOLOGICAL INHIBITION OF MRK/ZAK KINASE FOR THE TREATMENT OF MEDULLOBLASTOMA","year":2015,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Medulloblastoma; Cancer research; Cell cycle; Kinase; Cell cycle checkpoint; Malignancy; Medicine; Cell; Biology; Chemistry; Internal medicine; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001530671,0.0001116518,0.0003820647,0.00005184796,0.00002884079,0.000001738354,0.00005179862,0.0001064648,0.0001425682],"category_scores_gemma":[0.00005311012,0.00006718736,0.0001400991,0.00009726902,0.0001209869,0.00001907793,0.00001455487,0.00006913969,0.000004082729],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001872332,"about_ca_system_score_gemma":0.0002461504,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003799315,"about_ca_topic_score_gemma":0.00003203949,"domain_scores_codex":[0.9991822,0.00007369362,0.0002623343,0.000173593,0.0001403285,0.0001678105],"domain_scores_gemma":[0.9990667,0.0003809667,0.0001541081,0.000154226,0.0001334922,0.0001104824],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.003999106,0.001537733,0.00004458423,0.00001765308,0.00009163174,0.00006591074,0.0006293632,0.00002051976,0.8990069,0.0008689398,0.004598545,0.08911911],"study_design_scores_gemma":[0.009260095,0.03375801,0.0001028004,0.000007685986,0.0002443786,0.00007136341,0.0002252962,0.0002790488,0.6508231,0.0004805307,0.3046991,0.00004863643],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9903883,0.0005802892,0.0005817421,0.005616435,0.0009589971,0.00118324,0.00003627815,0.00002723641,0.0006275325],"genre_scores_gemma":[0.9968267,0.0004371032,0.0005393444,0.001517788,0.0003727328,0.0002210101,0.00001065413,0.00001592246,0.00005872756],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.3001006,"threshold_uncertainty_score":0.2739821,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06553781742733895,"score_gpt":0.3649615139227598,"score_spread":0.2994236964954208,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}