{"id":"W2097499299","doi":"10.1093/neuonc/nov061.81","title":"MB-05 * PHARMACOLOGICAL INHIBITION OF MRK/ZAK KINASE FOR THE TREATMENT OF MEDULLOBLASTOMA","year":2015,"lang":"en","type":"article","venue":"Neuro-Oncology","topic":"Cancer Mechanisms and Therapy","field":"Medicine","cited_by":0,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Manitoba","funders":"","keywords":"Medulloblastoma; Cancer research; Cell cycle; Kinase; Cell cycle checkpoint; Malignancy; Medicine; Cell; Biology; Chemistry; Internal medicine; Cell biology; Biochemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000127051,0.0004618167,0.0003971056,0.0002793654,0.0002055397,0.0002569266,0.0002724966,0.0002999576,0.003116176],"category_scores_gemma":[0.00006334834,0.000153027,0.0003425588,0.0002199576,0.0001781287,0.0001306538,0.0001608756,0.001012333,0.0008457389],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003829209,"about_ca_system_score_gemma":0.0005172776,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001128156,"about_ca_topic_score_gemma":0.002432464,"domain_scores_codex":[0.9999173,0.00001260702,0.000007707754,0.00001118253,0.00002105813,0.00003008099],"domain_scores_gemma":[0.9999739,0.00000271635,0.000005700274,0.000002073448,0.000003125092,0.00001243735],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002045476,0.001036839,0.000434053,0.0003778108,0.00008059968,0.0001764526,0.00004476471,0.0005904736,0.962409,0.0006681716,0.002365958,0.02977034],"study_design_scores_gemma":[0.00202853,0.01969406,0.01196188,0.00005578464,0.0001657611,0.001298404,0.00008985766,0.003117511,0.9181016,0.0002164495,0.04323414,0.0000360462],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9686373,0.01246446,0.003913702,0.0007004659,0.0003246027,0.0005228354,0.00167174,0.0007270177,0.01103792],"genre_scores_gemma":[0.9811249,0.005443464,0.003897337,0.0001809797,0.00003148785,0.0003467421,0.002102096,0.00002737578,0.006845636],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003116176,"threshold_uncertainty_score":0.01042461,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.06553781742733895,"score_gpt":0.3649615139227598,"score_spread":0.2994236964954208,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}