{"id":"W2097524729","doi":"10.2174/156652310793180698","title":"Retinal Blinding Disorders and Gene Therapy - Molecular and Clinical Aspects","year":2010,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Retinitis pigmentosa; Blinding; Retinal Disorder; Retinal degeneration; Retina; Retinal; Genetic enhancement; Retinal pigment epithelium; Biology; Gene therapy of the human retina; Macular degeneration; Bioinformatics; Gene; Neuroscience; Medicine; Genetics; Clinical trial; Ophthalmology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003303832,0.0004021447,0.0005139528,0.001265269,0.0002362869,0.001011349,0.0003270928,0.001128999,0.002832464],"category_scores_gemma":[0.0003811858,0.0001050381,0.0003614496,0.0009429816,0.0006941632,0.001000162,0.0005071292,0.001174699,0.001026575],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006314324,"about_ca_system_score_gemma":0.0006053731,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0004089857,"about_ca_topic_score_gemma":0.0005712229,"domain_scores_codex":[0.9997841,0.00003439223,0.00003738336,0.00004349982,0.0000743632,0.00002626723],"domain_scores_gemma":[0.9998589,0.00005246852,0.0000260555,0.000008955075,0.00003559205,0.00001800388],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00020902,0.0001443578,0.001207488,0.008127959,0.00007876467,0.002809486,0.0002755204,0.0004095117,0.02149357,0.03910885,0.05236869,0.8737667],"study_design_scores_gemma":[0.00001566021,0.000308374,0.00330966,0.001318157,0.00005469111,0.0287223,0.0001806504,0.0001589329,0.003481405,0.007908421,0.9545152,0.00002655997],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.001315372,0.9875703,0.0007935564,0.001603201,0.001122116,0.0000194679,0.00002881029,0.00002555838,0.007521666],"genre_scores_gemma":[0.01473328,0.9677923,0.002122195,0.002452004,0.002987447,0.00004273666,0.0001076662,0.00001140732,0.009751036],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.002832464,"threshold_uncertainty_score":0.009475589,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05041948407339245,"score_gpt":0.3799895948101813,"score_spread":0.3295701107367889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}