{"id":"W2097524729","doi":"10.2174/156652310793180698","title":"Retinal Blinding Disorders and Gene Therapy - Molecular and Clinical Aspects","year":2010,"lang":"en","type":"review","venue":"Current Gene Therapy","topic":"Retinal Development and Disorders","field":"Biochemistry, Genetics and Molecular Biology","cited_by":11,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"","keywords":"Retinitis pigmentosa; Blinding; Retinal Disorder; Retinal degeneration; Retina; Retinal; Genetic enhancement; Retinal pigment epithelium; Biology; Gene therapy of the human retina; Macular degeneration; Bioinformatics; Gene; Neuroscience; Medicine; Genetics; Clinical trial; Ophthalmology","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":false,"about_ca":true,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.000517127,0.0006729395,0.0009650382,0.0001275016,0.0001507835,0.00009978242,0.0003535809,0.0006060547,0.00002308952],"category_scores_gemma":[0.00004845569,0.0005433685,0.0004356852,0.0001485601,0.0003000759,0.000005925603,0.0001707174,0.0005896043,0.000008815721],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001049254,"about_ca_system_score_gemma":0.000264467,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000002824228,"about_ca_topic_score_gemma":0.000005607671,"domain_scores_codex":[0.9974154,0.0002610871,0.0006566187,0.001007795,0.0002185916,0.0004405254],"domain_scores_gemma":[0.9988261,0.0000430145,0.0003460326,0.0005051778,0.00005324746,0.0002263869],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00007869759,0.0001163624,0.0005171192,0.0002642062,0.0002088326,0.000003219761,0.00001804969,4.859143e-8,0.001396577,0.0000307281,0.0001685247,0.9971976],"study_design_scores_gemma":[0.001183773,0.0004109794,0.0001901873,0.0003884416,0.00009396999,0.00003545648,0.000005194413,0.000001124563,0.0009619549,0.000222511,0.9958054,0.0007009868],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.06495937,0.9329756,0.0001542124,0.00004333364,0.0007731785,0.0008388006,0.00001818388,0.00002216273,0.0002151229],"genre_scores_gemma":[0.0007987148,0.9975016,0.0004140116,0.00007970932,0.0004865145,0.00007569794,0.000485155,0.0001015371,0.00005705167],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9964966,"threshold_uncertainty_score":0.9997018,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05041948407339245,"score_gpt":0.3799895948101813,"score_spread":0.3295701107367889,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}