{"id":"W2097536855","doi":"10.1128/jb.188.6.2048-2055.2006","title":"Requirement of <i>Staphylococcus aureus</i> ATP-Binding Cassette-ATPase FhuC for Iron-Restricted Growth and Evidence that It Functions with More than One Iron Transporter","year":2006,"lang":"en","type":"article","venue":"Journal of Bacteriology","topic":"Antimicrobial Resistance in Staphylococcus","field":"Medicine","cited_by":99,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Canadian Institutes of Health Research; Ontario Innovation Trust","keywords":"Biology; Complementation; Mutant; Staphylococcus aureus; Permease; Ferrichrome; ATP-binding cassette transporter; Transporter; ATPase; Biochemistry; Siderophore; Strain (injury); Ferrous; Membrane transport protein; Mutation; Escherichia coli; Bacteria; Enzyme; Chemistry; Genetics; Gene; Anatomy; Bacterial outer membrane","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.000135156,0.0002791729,0.000220477,0.0001601003,0.0001575683,0.0004441671,0.0002722296,0.0003054966,0.0005838759],"category_scores_gemma":[0.0004199388,0.0001349205,0.0002138565,0.00009015427,0.000214012,0.0002136862,0.0003768608,0.000330008,0.0004441128],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002968512,"about_ca_system_score_gemma":0.0003360492,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.003366288,"about_ca_topic_score_gemma":0.002985522,"domain_scores_codex":[0.9997008,0.00004368318,0.00003533479,0.00003496275,0.0001283298,0.00005701644],"domain_scores_gemma":[0.9996437,0.00008153408,0.00007311016,0.00005135184,0.0000727132,0.00007758534],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002628114,0.0000140818,0.0005538903,0.00001780952,0.000001913041,0.00008158378,0.00001811342,0.00002487513,0.9982053,0.00007978812,0.00002644249,0.0009499005],"study_design_scores_gemma":[0.000005180161,0.0001338065,0.01193406,0.000008684276,0.00001096314,0.001391364,0.00007525723,0.001359041,0.9832607,0.00006263266,0.001748273,0.00001000429],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9936953,0.0005353101,0.00345123,0.0002194048,0.00001727393,0.0000167394,0.0002226715,0.00008381737,0.001758228],"genre_scores_gemma":[0.9958975,0.0001636027,0.002703494,0.00004968195,0.000006764285,0.00001194864,0.0004026839,0.00002186672,0.0007424478],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003366288,"threshold_uncertainty_score":0.006693423,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03333511241175539,"score_gpt":0.2766983578765256,"score_spread":0.2433632454647702,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}