{"id":"W2097546772","doi":"10.1534/genetics.114.161513","title":"DNA Helicase HIM-6/BLM Both Promotes MutSγ-Dependent Crossovers and Antagonizes MutSγ-Independent Interhomolog Associations During <i>Caenorhabditis elegans</i> Meiosis","year":2014,"lang":"en","type":"article","venue":"Genetics","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Office of Research Infrastructure Programs, National Institutes of Health; Canadian Institutes of Health Research; National Institute of General Medical Sciences; U.S. Bureau of Land Management; National Institutes of Health; National Human Genome Research Institute; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Howard Hughes Medical Institute","keywords":"Biology; Homologous recombination; Meiosis; Chiasma; Homologous chromosome; Genetics; Helicase; Caenorhabditis elegans; DNA; DNA repair; Chromosomal crossover; RecQ helicase; RNA Helicase A; Cell biology; Genome instability; Gene; DNA damage; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003633246,0.0003734845,0.000325321,0.00008503548,0.0002963914,0.0001544782,0.0003517331,0.000363395,0.00003509344],"category_scores_gemma":[0.0002076356,0.0004027268,0.0001510527,0.0001016124,0.0001306838,0.00001225685,0.0004793416,0.0002018259,0.00002251533],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007798851,"about_ca_system_score_gemma":0.00007563119,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0000389307,"about_ca_topic_score_gemma":0.000337983,"domain_scores_codex":[0.9976274,0.0001611073,0.0004366869,0.0007951806,0.0003638682,0.000615782],"domain_scores_gemma":[0.9986793,0.00003780648,0.0002266662,0.0006752965,0.0001328983,0.0002479925],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00003819621,0.000131487,0.006923574,0.00004345854,0.0001523994,0.0000222028,0.0001877028,0.0000382511,0.9904385,0.000106264,0.0003684001,0.001549534],"study_design_scores_gemma":[0.001369879,0.0005239848,0.008658244,0.00002372147,0.00009696996,0.0001694573,0.0001355953,0.0001462178,0.9841037,0.0003642736,0.003908946,0.0004990221],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9957147,0.000570616,0.001967726,0.000208959,0.000380344,0.0003975039,0.0002036958,0.00008072619,0.0004757515],"genre_scores_gemma":[0.9954203,0.0004453629,0.002289669,0.0003784737,0.0003661225,0.00005580821,0.0001559918,0.00008098641,0.0008073215],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.006334841,"threshold_uncertainty_score":0.9998425,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005494939462227666,"score_gpt":0.2203619889558406,"score_spread":0.2148670494936129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}