{"id":"W2097546772","doi":"10.1534/genetics.114.161513","title":"DNA Helicase HIM-6/BLM Both Promotes MutSγ-Dependent Crossovers and Antagonizes MutSγ-Independent Interhomolog Associations During <i>Caenorhabditis elegans</i> Meiosis","year":2014,"lang":"en","type":"article","venue":"Genetics","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":38,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"Office of Research Infrastructure Programs, National Institutes of Health; Canadian Institutes of Health Research; National Institute of General Medical Sciences; U.S. Bureau of Land Management; National Institutes of Health; National Human Genome Research Institute; Eunice Kennedy Shriver National Institute of Child Health and Human Development; Howard Hughes Medical Institute","keywords":"Biology; Homologous recombination; Meiosis; Chiasma; Homologous chromosome; Genetics; Helicase; Caenorhabditis elegans; DNA; DNA repair; Chromosomal crossover; RecQ helicase; RNA Helicase A; Cell biology; Genome instability; Gene; DNA damage; RNA","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001433685,0.0003427675,0.0002058323,0.0002178886,0.0001616948,0.000297781,0.0003594216,0.0002726182,0.00115145],"category_scores_gemma":[0.0001391397,0.0001745993,0.0002026783,0.00005818863,0.0002247646,0.0001562661,0.0002531525,0.0005487893,0.0004480661],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003168581,"about_ca_system_score_gemma":0.0001935639,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006640874,"about_ca_topic_score_gemma":0.001200919,"domain_scores_codex":[0.9998203,0.00002459599,0.00002252275,0.00003218012,0.00005628737,0.00004418071],"domain_scores_gemma":[0.999782,0.00002536245,0.00005414569,0.00002505165,0.0000123012,0.0001012105],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00008376248,0.00002757943,0.0001617253,0.00001871555,0.000002867395,0.00002992856,0.000005668802,0.0000415364,0.99901,0.0000619119,0.00002664444,0.0005298108],"study_design_scores_gemma":[0.00001678166,0.0001524552,0.002688354,0.000004827337,0.000006271668,0.0001592863,0.00001421802,0.0007475517,0.9945818,0.00001913419,0.001606387,0.000002878444],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959601,0.0008353246,0.001445846,0.00007479725,0.00001967591,0.00001755581,0.000146063,0.0001300762,0.001370651],"genre_scores_gemma":[0.9964186,0.0002515296,0.00113305,0.00002845553,0.000006006541,0.00001015548,0.0001699186,0.00001767146,0.001964614],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00115145,"threshold_uncertainty_score":0.00385195,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.005494939462227666,"score_gpt":0.2203619889558406,"score_spread":0.2148670494936129,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}