{"id":"W2097549367","doi":"10.3899/jrheum.140094","title":"The Current and Future Status of Biomarkers in Osteoarthritis","year":2014,"lang":"en","type":"letter","venue":"The Journal of Rheumatology","topic":"Osteoarthritis Treatment and Mechanisms","field":"Medicine","cited_by":23,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of Arthritis and Musculoskeletal and Skin Diseases","keywords":"Medicine; Osteoarthritis; Biomarker; Cartilage; Synovitis; Rheumatoid arthritis; Cartilage oligomeric matrix protein; Synovial fluid; Arthritis; Internal medicine; Hyaline cartilage; Pathology; Articular cartilage","routes":{"ca_aff":false,"ca_fund":false,"ca_venue":true,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.01706908,0.001562465,0.003474636,0.005426743,0.002068805,0.009318333,0.003226588,0.01165473,0.005599398],"category_scores_gemma":[0.03673707,0.0007750368,0.001576686,0.0039868,0.005040069,0.01353943,0.0032424,0.01494697,0.002337426],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.003255602,"about_ca_system_score_gemma":0.00555409,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001517047,"about_ca_topic_score_gemma":0.002502642,"domain_scores_codex":[0.9914901,0.002354746,0.001968959,0.000901964,0.002698975,0.0005851819],"domain_scores_gemma":[0.9365502,0.03318013,0.003446502,0.001109378,0.02076914,0.004944643],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"not_applicable","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0003492227,0.00007744539,0.001545135,0.005509076,0.0001486939,0.0003144875,0.0003204319,0.0001641931,0.0004770091,0.01471959,0.5447587,0.431616],"study_design_scores_gemma":[0.00003599754,0.0001294299,0.001099776,0.002802096,0.00009144945,0.0004456561,0.0003328379,0.0001884103,0.0001354607,0.008586115,0.9860934,0.00005927496],"study_design_candidate":"not_applicable","study_design_consensus":"not_applicable","genre_codex":"review","genre_gemma":"commentary","genre_scores_codex":[0.0002025401,0.7403834,0.0005140945,0.1230121,0.1345691,0.00001031622,0.000047188,0.00005089492,0.001210465],"genre_scores_gemma":[0.002778166,0.5935265,0.001117835,0.0551385,0.345819,0.00002688853,0.00008732206,0.00005317587,0.001452549],"genre_candidate":"commentary","genre_consensus":null,"teacher_disagreement_score":0.01706908,"threshold_uncertainty_score":0.09027094,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01033526922390791,"score_gpt":0.2528963204461641,"score_spread":0.2425610512222562,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}