{"id":"W2097565956","doi":"10.1038/embor.2011.243","title":"ChAM, a novel motif that mediates PALB2 intrinsic chromatin binding and facilitates DNA repair","year":2011,"lang":"en","type":"article","venue":"EMBO Reports","topic":"DNA Repair Mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":57,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université Laval; Hôtel-Dieu de Québec","funders":"Canadian Institutes of Health Research; Fonds Québécois de la Recherche sur la Nature et les Technologies; Breast Cancer Campaign; Cancer Research UK; Wellcome Trust","keywords":"Chromatin; PALB2; RAD51; Biology; Homologous recombination; Genetics; DNA damage; DNA repair; DNA; Cell biology; Molecular biology; Gene; Mutation","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002863838,0.0004298851,0.0004857354,0.0002182735,0.0008048893,0.0006964072,0.0006012769,0.0009570509,0.008538648],"category_scores_gemma":[0.000524946,0.0003180581,0.0003202168,0.0001751101,0.0003932671,0.0005422888,0.0005491417,0.001065651,0.003035691],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005262671,"about_ca_system_score_gemma":0.0003706333,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003793912,"about_ca_topic_score_gemma":0.001243049,"domain_scores_codex":[0.9998168,0.00003323399,0.000009097822,0.00005432519,0.00005992813,0.0000266381],"domain_scores_gemma":[0.999749,0.0000524515,0.00004465835,0.00003721604,0.00001738927,0.00009924654],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003146083,0.00003207656,0.0002413834,0.00006414629,0.000006810358,0.0001976314,0.00001883986,0.0001653146,0.9942624,0.001157229,0.0003438071,0.003195853],"study_design_scores_gemma":[0.00007317201,0.0002196093,0.002166929,0.000009710774,0.00001049128,0.001100712,0.00003947191,0.002308151,0.9810473,0.0004844795,0.0125172,0.00002268614],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9358189,0.003367829,0.04354415,0.0006394788,0.0005000239,0.0001774162,0.0007755565,0.001379876,0.01379687],"genre_scores_gemma":[0.9810413,0.0002838089,0.01031488,0.0001681608,0.00004347212,0.00005998025,0.0005760507,0.0001059563,0.007406435],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.008538648,"threshold_uncertainty_score":0.02856457,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0227939144021027,"score_gpt":0.2237896153957495,"score_spread":0.2009957009936468,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}