{"id":"W2097566310","doi":"10.1128/aac.01599-07","title":"Effects of Subinhibitory Concentrations of Antibiotics on SOS and DNA Repair Gene Expression in <i>Staphylococcus aureus</i>","year":2008,"lang":"en","type":"article","venue":"Antimicrobial Agents and Chemotherapy","topic":"RNA and protein synthesis mechanisms","field":"Biochemistry, Genetics and Molecular Biology","cited_by":100,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of British Columbia","funders":"McGill University; Dartmouth College","keywords":"SOS response; Gene; Biology; Antibiotics; Transcription (linguistics); Staphylococcus aureus; Mutant; DNA repair; DNA; Gene expression; Reporter gene; Microbiology; Fusion gene; Regulation of gene expression; Antibacterial agent; Genetics; Bacteria","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002257312,0.0004179135,0.0004465865,0.000179641,0.000113401,0.0003103616,0.0002811698,0.0002763765,0.0009442074],"category_scores_gemma":[0.000319428,0.0002151352,0.0002437513,0.0001944247,0.0002485209,0.0001661949,0.0001958289,0.0006094864,0.0003121149],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0004565578,"about_ca_system_score_gemma":0.0002513701,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001882749,"about_ca_topic_score_gemma":0.002372702,"domain_scores_codex":[0.9995853,0.00009746026,0.00005766602,0.00006206032,0.0001153273,0.00008218623],"domain_scores_gemma":[0.9995549,0.0001825652,0.00008724326,0.00004504951,0.0000486239,0.00008157762],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001439674,0.00004577406,0.00008850924,0.00002221908,0.000002737331,0.00001450259,0.00001347938,0.00004335442,0.9991066,0.00003336001,0.0000260759,0.0004594091],"study_design_scores_gemma":[0.000008057556,0.0003204225,0.001776505,0.000004035683,0.000006820989,0.00004304749,0.00002053611,0.0003631282,0.9970374,0.00001722707,0.0003985559,0.000004278867],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9955595,0.0009617183,0.001053329,0.0001281646,0.00004196322,0.00003490601,0.0006484236,0.00006431063,0.001507659],"genre_scores_gemma":[0.9926797,0.0007256772,0.003301315,0.0001017391,0.00002022722,0.00006425567,0.001144256,0.00004836444,0.001914467],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001882749,"threshold_uncertainty_score":0.003743529,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006507836798910881,"score_gpt":0.2119260798021763,"score_spread":0.2054182430032654,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}