{"id":"W2097710619","doi":"10.1128/mcb.24.5.2190-2201.2004","title":"Site-Selective Regulation of Platelet-Derived Growth Factor β Receptor Tyrosine Phosphorylation by T-Cell Protein Tyrosine Phosphatase","year":2004,"lang":"en","type":"article","venue":"Molecular and Cellular Biology","topic":"Protein Tyrosine Phosphatases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":98,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Deutsche Forschungsgemeinschaft; Swedish Cancer Foundation; Ludwig Institute for Cancer Research","keywords":"Platelet-derived growth factor receptor; Biology; Protein tyrosine phosphatase; Tyrosine phosphorylation; Autophosphorylation; Receptor tyrosine kinase; Phosphorylation; Cell biology; Tyrosine kinase; Tyrosine; Molecular biology; Receptor; Signal transduction; Biochemistry; Growth factor; Protein kinase A","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0001536415,0.0003903034,0.0003738751,0.00008173657,0.0001153119,0.00002395663,0.0002031287,0.0004127219,0.00004699879],"category_scores_gemma":[0.0001296881,0.0003905799,0.0001262179,0.0002280122,0.0002813793,0.00001648976,0.0001549056,0.0001586552,0.00001465802],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00004483487,"about_ca_system_score_gemma":0.0001003243,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002391356,"about_ca_topic_score_gemma":0.000007804409,"domain_scores_codex":[0.9980947,0.000130569,0.0004519481,0.0007422249,0.0001596967,0.0004208728],"domain_scores_gemma":[0.9988878,0.00001153367,0.000309689,0.0004244394,0.0002174033,0.0001491012],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0003825236,0.0001805806,0.0003083314,0.00005921935,0.00005909031,0.000004319753,0.00003881477,0.00002936667,0.9954343,0.002387626,0.0002984526,0.0008174109],"study_design_scores_gemma":[0.002273896,0.001072424,0.0001993431,0.00003000826,0.00003008295,0.00000631741,0.0000110324,0.0000118695,0.9931353,0.0009424352,0.001868284,0.0004189589],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9246731,0.03623914,0.03715716,0.0001455006,0.0000838263,0.0008642005,0.0007434358,0.00003274724,0.00006085006],"genre_scores_gemma":[0.9900957,0.0002564133,0.003006076,0.0001459478,0.00005869733,0.00008117963,0.006216098,0.00005850877,0.00008138171],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.06542256,"threshold_uncertainty_score":0.9998546,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00456459735828295,"score_gpt":0.2021998387609331,"score_spread":0.1976352414026501,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}