{"id":"W2097771941","doi":"10.1084/jem.20071331","title":"An HIV-1 clade C DNA prime, NYVAC boost vaccine regimen induces reliable, polyfunctional, and long-lasting T cell responses","year":2008,"lang":"en","type":"article","venue":"The Journal of Experimental Medicine","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":294,"is_retracted":false,"has_abstract":true,"ca_institutions":"Sanofi (Canada)","funders":"","keywords":"Immunogenicity; Immunogen; Virology; ELISPOT; DNA vaccination; HIV vaccine; Epitope; Biology; T cell; CD8; Immunology; Antigen; Medicine; Immune system; Antibody; Vaccine trial; Vaccination; Immunization","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004555738,0.0004432958,0.0005929396,0.0001850312,0.0001026042,0.0002433843,0.0002465519,0.0004260062,0.001525747],"category_scores_gemma":[0.0005437068,0.0001625596,0.00009672566,0.0001367916,0.0003129462,0.0002714694,0.000130151,0.0007251453,0.0003084986],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002275537,"about_ca_system_score_gemma":0.0002794485,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002857181,"about_ca_topic_score_gemma":0.0005474537,"domain_scores_codex":[0.9997529,0.00008011411,0.00001324295,0.00005301925,0.00004734845,0.00005343499],"domain_scores_gemma":[0.9998056,0.0000505076,0.00004662701,0.00001970206,0.00001524958,0.00006231677],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0776225,0.02161646,0.008149328,0.0006272877,0.0001710969,0.000196798,0.0001316668,0.001658699,0.7659726,0.0002776426,0.001739002,0.1218369],"study_design_scores_gemma":[0.03635987,0.6763627,0.05348831,0.00007106298,0.0002191105,0.001377795,0.00008122909,0.003379195,0.2205952,0.0001742471,0.007850824,0.00004050973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979919,0.0005357875,0.0003088632,0.00003800219,0.00002490365,0.0001942557,0.0001048413,0.00003696385,0.0007646375],"genre_scores_gemma":[0.9967092,0.0003294041,0.001089869,0.0001165269,0.00005212815,0.0001875639,0.0004214208,0.00001118915,0.001082678],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001525747,"threshold_uncertainty_score":0.005104184,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02769200610385697,"score_gpt":0.2981105814790007,"score_spread":0.2704185753751437,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}