{"id":"W2097827010","doi":"10.1093/emboj/cdg218","title":"Stimulation of preadipocyte differentiation by steroid through targeting of an HDAC1 complex","year":2003,"lang":"en","type":"article","venue":"The EMBO Journal","topic":"Histone Deacetylase Inhibitors Research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":140,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"Canadian Institutes of Health Research; McKnight Foundation","keywords":"Corepressor; HDAC1; Biology; Ccaat-enhancer-binding proteins; Histone deacetylase; Glucocorticoid receptor; Adipogenesis; Histone; Endocrinology; Cell biology; Cellular differentiation; Internal medicine; Glucocorticoid; Nuclear receptor; Molecular biology; Transcription factor; Biochemistry; Nuclear protein; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001498085,0.0003606373,0.0002565034,0.0002332608,0.0003526451,0.0004462333,0.0002494272,0.0001618509,0.003092532],"category_scores_gemma":[0.0001085568,0.0002254673,0.0003238108,0.0001914319,0.0002765516,0.0002057512,0.0003164948,0.0007447745,0.0009202329],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001061219,"about_ca_system_score_gemma":0.0003761786,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001543155,"about_ca_topic_score_gemma":0.00493949,"domain_scores_codex":[0.9998926,0.00001011736,0.000007086468,0.00002251109,0.00002725484,0.00004042462],"domain_scores_gemma":[0.999912,0.00001209011,0.0000154651,0.00001132002,0.00001140304,0.00003763756],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001564863,0.00001152025,0.0001231915,0.00003213732,0.000004814039,0.00002880427,0.00001036822,0.00002328633,0.9979152,0.0001841592,0.00008687963,0.001423287],"study_design_scores_gemma":[0.00002167138,0.00004717484,0.003508729,0.000003415855,0.000008654158,0.00006718036,0.00002067964,0.0001951695,0.9923837,0.00003550161,0.003705286,0.00000286973],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9713978,0.01009315,0.006699634,0.0009013442,0.0002794469,0.00008272939,0.001262473,0.0003406824,0.008942639],"genre_scores_gemma":[0.9861766,0.002414673,0.002136098,0.0001256004,0.00003998254,0.00002902297,0.0009436451,0.00006100879,0.008073369],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.003092532,"threshold_uncertainty_score":0.01034552,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02091440960876132,"score_gpt":0.3008371083376086,"score_spread":0.2799226987288472,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}