{"id":"W2097841397","doi":"10.1002/chem.201301590","title":"A Platinum(II) Phenylphenanthroimidazole with an Extended Side‐Chain Exhibits Slow Dissociation from a <i>c‐Kit</i> G‐Quadruplex Motif","year":2013,"lang":"en","type":"article","venue":"Chemistry - A European Journal","topic":"DNA and Nucleic Acid Chemistry","field":"Biochemistry, Genetics and Molecular Biology","cited_by":33,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University","funders":"Canadian Institutes of Health Research","keywords":"G-quadruplex; Chemistry; HeLa; Surface plasmon resonance; Moiety; Side chain; Stereochemistry; Telomere; Telomerase; Platinum; Dissociation (chemistry); Combinatorial chemistry; Biophysics; DNA; Biochemistry; Biology; Cell; Nanotechnology; Catalysis; Gene; Materials science","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.0003372261,0.000463697,0.0003094419,0.00002035108,0.0004859101,0.0002545456,0.0006294531,0.0001619956,0.0006917521],"category_scores_gemma":[0.0001303106,0.0004001172,0.0001739618,0.0001134049,0.0001866829,0.00004699224,0.0002307826,0.0005205288,0.00006033734],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00005915899,"about_ca_system_score_gemma":0.0001281656,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00001416092,"about_ca_topic_score_gemma":0.000002301912,"domain_scores_codex":[0.9976138,0.0001496491,0.0005436547,0.0006840561,0.0004023929,0.0006063766],"domain_scores_gemma":[0.9980264,0.00001720308,0.0004777897,0.000681038,0.0002515693,0.0005459717],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001336251,0.0002362407,0.0005030087,0.00002272773,0.0001328594,0.00008986772,0.0002837475,0.00005057843,0.9869772,7.703492e-7,0.00516876,0.006400642],"study_design_scores_gemma":[0.003275962,0.0004479136,0.005402096,0.0001583045,0.0001026085,0.0005127791,0.00125022,0.001239127,0.9775671,0.0001455875,0.008927522,0.0009708197],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895602,0.0002916661,0.0009395545,0.0002559761,0.0001004075,0.000136794,0.00005631017,0.00006204116,0.008597072],"genre_scores_gemma":[0.9924696,0.00007802185,0.0022687,0.0002856987,0.00168452,0.0000121557,0.000486482,0.0001303127,0.002584477],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.009410113,"threshold_uncertainty_score":0.9998451,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.006374626300556721,"score_gpt":0.1999556824376969,"score_spread":0.1935810561371402,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}