{"id":"W2097985864","doi":"10.1111/j.1439-0531.2012.02063.x","title":"Developmental and Epigenetic Anomalies in Cloned Cattle","year":2012,"lang":"en","type":"review","venue":"Reproduction in Domestic Animals","topic":"Reproductive Biology and Fertility","field":"Medicine","cited_by":95,"is_retracted":false,"has_abstract":true,"ca_institutions":"Cegep de Saint Hyacinthe; Université de Montréal","funders":"Canada Research Chairs","keywords":"Genomic imprinting; Biology; Reprogramming; Epigenetics; Somatic cell nuclear transfer; DNA methylation; Genetics; Differentially methylated regions; Imprinting (psychology); Somatic cell; Embryo; Methylation; Offspring; Gene; Allele; Gene expression; Embryogenesis; Blastocyst; Pregnancy","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow"],"consensus_categories":[],"category_scores_codex":[0.001387592,0.0003643962,0.001576311,0.0004136777,0.00004900562,0.000009301675,0.00008010265,0.0003749086,0.0001161868],"category_scores_gemma":[0.001175079,0.000298123,0.0001056074,0.0005253408,0.0003063766,0.00006853411,0.00009339967,0.0004659709,0.00009517003],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003307137,"about_ca_system_score_gemma":0.0003148532,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00004447879,"about_ca_topic_score_gemma":0.000009598362,"domain_scores_codex":[0.9971388,0.0002809356,0.0008683748,0.001205294,0.0001318346,0.0003747485],"domain_scores_gemma":[0.9990294,0.0001300433,0.0002198683,0.0004651174,0.00005372494,0.0001018554],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.0003520272,0.0003244658,0.03243909,0.01030638,0.000102651,0.00005995284,0.0002966747,2.644159e-7,0.00005780986,0.00005517545,0.00003294845,0.9559726],"study_design_scores_gemma":[0.0003819836,0.0001303049,0.5301691,0.002573144,0.0003489467,0.002970361,0.00007356064,2.596742e-7,0.00001815015,0.0001408579,0.462857,0.0003363276],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.02686538,0.9709257,0.000004948282,0.00009057149,0.0003244521,0.001278285,0.000005985208,0.00003616547,0.0004684834],"genre_scores_gemma":[0.04456108,0.9531946,0.0009054202,0.000009255168,0.0004479852,0.0002070773,0.00003689217,0.00003478151,0.0006028706],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.9556363,"threshold_uncertainty_score":0.9999471,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.08875675663182567,"score_gpt":0.3698202438176449,"score_spread":0.2810634871858192,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}