{"id":"W2098068023","doi":"10.1242/jcs.045351","title":"G2 histone methylation is required for the proper segregation of chromosomes","year":2009,"lang":"en","type":"article","venue":"Journal of Cell Science","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":35,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Calgary; University of Alberta","funders":"","keywords":"Biology; Kinetochore; EZH2; Mitosis; Chromatin; Heterochromatin; Methylation; Cell biology; Centromere; Spindle checkpoint; Aurora B kinase; Histone methylation; Chromosome segregation; Mitotic exit; Histone; Prophase; Genetics; DNA methylation; Spindle apparatus; Chromosome; Cell division; Cell; Meiosis; DNA; Gene expression","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0009309658,0.00004853296,0.00007650394,0.00004877675,0.0000924595,0.00001792088,0.0001994841,0.00003662403,0.000004662274],"category_scores_gemma":[0.0001441047,0.00003028598,0.00006474114,0.0001482041,0.0001415841,0.00001544071,0.00001310685,0.00003381021,3.166452e-7],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001736579,"about_ca_system_score_gemma":0.0001598995,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000001320614,"about_ca_topic_score_gemma":6.354352e-7,"domain_scores_codex":[0.9993165,0.00001773275,0.000241051,0.00009280026,0.0002418898,0.00009006894],"domain_scores_gemma":[0.9990182,0.00001965321,0.0003554304,0.0001294198,0.0004433686,0.0000339163],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002760032,0.00002344532,0.00006373764,0.000004183123,0.000002895272,7.606751e-8,0.0001162855,0.0002398278,0.9865721,0.00006528505,0.0001146518,0.01276993],"study_design_scores_gemma":[0.0002208156,0.0005483626,0.002802565,0.000007020913,0.00001534887,0.000001652347,0.0000277086,0.0005015046,0.9901127,0.001120261,0.00460124,0.00004076949],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9575676,0.00300812,0.03771832,0.0008495547,0.0001757151,0.0001440771,0.000001789231,9.115705e-7,0.0005339069],"genre_scores_gemma":[0.9938369,0.0003422626,0.005322881,0.00007497221,0.0001065049,8.336586e-7,0.000001110236,0.000002733834,0.0003118239],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03626927,"threshold_uncertainty_score":0.1235026,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01848758368395763,"score_gpt":0.3061392607634504,"score_spread":0.2876516770794927,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}