{"id":"W2098141357","doi":"10.1261/rna.038497.113","title":"Annealing to sequences within the primer binding site loop promotes an HIV-1 RNA conformation favoring RNA dimerization and packaging","year":2013,"lang":"en","type":"article","venue":"RNA","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; Jewish General Hospital","funders":"Canadian Institutes of Health Research","keywords":"RNA; Guide RNA; Biology; Untranslated region; Mutant; Transfer RNA; Transcription (linguistics); Cell biology; Biophysics; Molecular biology; Biochemistry; Gene; CRISPR","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002290695,0.0002432484,0.0002398944,0.00007484023,0.0001647224,0.0002987717,0.0001641485,0.0003383265,0.000980699],"category_scores_gemma":[0.0002811184,0.000214924,0.0004054884,0.00007327727,0.0002012483,0.0002032827,0.0002010645,0.0005277082,0.0003699266],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001338476,"about_ca_system_score_gemma":0.0001505342,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001759067,"about_ca_topic_score_gemma":0.000307947,"domain_scores_codex":[0.9997928,0.00004868633,0.00001465103,0.00005450343,0.00005272573,0.00003674209],"domain_scores_gemma":[0.9997402,0.00009445509,0.00006622855,0.00002617354,0.00002233497,0.00005067305],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002671478,0.00001020438,0.0001421083,0.00001000587,0.000002038339,0.00001397989,0.00001092834,0.00006833221,0.9993413,0.0000269482,0.000004964501,0.0003425583],"study_design_scores_gemma":[0.000006469216,0.0002886158,0.003219666,0.000003223268,0.000009376315,0.0001816995,0.00002043256,0.001167281,0.9946663,0.00004098649,0.0003898032,0.000006079115],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.996348,0.000277691,0.002717269,0.00002932211,0.000008414051,0.00001018516,0.00002146907,0.00004286763,0.0005447661],"genre_scores_gemma":[0.9968306,0.0001125028,0.002563355,0.00005546911,0.000003770874,0.000007679565,0.00005652195,0.00001155995,0.0003584925],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.000980699,"threshold_uncertainty_score":0.003280759,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01873186986840764,"score_gpt":0.2632199344797076,"score_spread":0.2444880646113,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}