{"id":"W2098155999","doi":"10.4049/jimmunol.1100269","title":"Single-Cell Analysis of the Human T Regulatory Population Uncovers Functional Heterogeneity and Instability within FOXP3+ Cells","year":2011,"lang":"en","type":"article","venue":"The Journal of Immunology","topic":"T-cell and B-cell Immunology","field":"Immunology and Microbiology","cited_by":73,"is_retracted":false,"has_abstract":true,"ca_institutions":"McGill University; McGill University Health Centre","funders":"Canadian Institutes of Health Research; McGill University Health Centre; McGill University","keywords":"FOXP3; Population; Instability; Cell; Cell biology; Biology; Genetics; Medicine; Immune system; Physics; Environmental health","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001714005,0.0001115918,0.0001933896,0.0002844683,0.0001020411,0.0002674815,0.0001380007,0.0001832477,0.0008695331],"category_scores_gemma":[0.000198643,0.00005531358,0.0001332796,0.0001715185,0.0001205064,0.00009945309,0.000123301,0.0002617847,0.0004097578],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007994684,"about_ca_system_score_gemma":0.00008615242,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003271904,"about_ca_topic_score_gemma":0.0003092086,"domain_scores_codex":[0.9999074,0.00001126907,0.000006823741,0.00003390476,0.00002399102,0.00001674219],"domain_scores_gemma":[0.9999137,0.00002796249,0.00001062501,0.00001601812,0.00001429975,0.00001745538],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.000146928,0.00001524635,0.00230068,0.00001714061,0.000005386044,0.00005160186,0.00003209574,0.00009278959,0.9924879,0.00004903121,0.00003688314,0.004764234],"study_design_scores_gemma":[0.00003065094,0.0009618878,0.06262817,0.00001209727,0.00009254686,0.00176816,0.0001229514,0.00450859,0.9239511,0.0002962748,0.005613094,0.0000144322],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853141,0.001638077,0.01152307,0.00004195606,0.00001213256,0.00004266492,0.0005522743,0.00008125968,0.0007944331],"genre_scores_gemma":[0.9933385,0.0004918523,0.004427454,0.00004482189,0.00001867574,0.00004736682,0.0009253794,0.0000212106,0.0006846466],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008695331,"threshold_uncertainty_score":0.002908885,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02522768787210582,"score_gpt":0.214211265629296,"score_spread":0.1889835777571902,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}