{"id":"W2098180946","doi":"10.1124/mol.59.4.716","title":"Cell-Specific Regulation of Human Aryl Hydrocarbon Receptor Expression by Transforming Growth Factor-β<sub>1</sub>","year":2001,"lang":"en","type":"article","venue":"Molecular Pharmacology","topic":"TGF-β signaling in diseases","field":"Biochemistry, Genetics and Molecular Biology","cited_by":70,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"","keywords":"SMAD; Aryl hydrocarbon receptor; Transfection; A549 cell; Molecular biology; Cell biology; Biology; Chemistry; Transforming growth factor; Cell; Gene; Biochemistry; Transcription factor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00008246751,0.000169893,0.0001320747,0.0001934903,0.000124425,0.0002895225,0.0001150945,0.0001231122,0.002233807],"category_scores_gemma":[0.0001030037,0.000126543,0.0001932714,0.0001612783,0.0001621531,0.0001296894,0.0001450154,0.0003641404,0.000854646],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002692706,"about_ca_system_score_gemma":0.0001804575,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001301616,"about_ca_topic_score_gemma":0.002396896,"domain_scores_codex":[0.9999024,0.00001600278,0.000006292177,0.00001284485,0.00001478854,0.00004772694],"domain_scores_gemma":[0.9999353,0.00002037868,0.00001038289,0.00001357564,0.000006667928,0.00001373273],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001709205,0.00002845094,0.0001762298,0.00001195552,0.000002889795,0.00004322669,0.00001782502,0.00003121196,0.9979487,0.0002546575,0.0000927301,0.001221192],"study_design_scores_gemma":[0.00002097988,0.0001707067,0.01113488,0.000003505047,0.00001074946,0.0002623988,0.00005933213,0.0005626125,0.9842143,0.0001158145,0.003440866,0.000003804823],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9912317,0.002021136,0.001433483,0.0001673894,0.00005483286,0.0000155625,0.0006324198,0.00007176682,0.004371761],"genre_scores_gemma":[0.9920551,0.001022148,0.0007759415,0.00008552748,0.00001776815,0.00001885859,0.0008500491,0.00002658686,0.005148031],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002233807,"threshold_uncertainty_score":0.007472813,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.008351494708319822,"score_gpt":0.2482501374545198,"score_spread":0.2398986427462,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}