{"id":"W2098203176","doi":"10.1186/bcr799","title":"Chemically induced DNA hypomethylation in breast carcinoma cells detected by the amplification of intermethylated sites","year":2004,"lang":"en","type":"article","venue":"Breast Cancer Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Western University","funders":"Canadian Institutes of Health Research; Canadian Breast Cancer Research Alliance","keywords":"DNA methylation; Biology; Methylation; Genome instability; Molecular biology; Illumina Methylation Assay; Epigenetics; Genetics; Cancer research; Gene; DNA; Gene expression; DNA damage","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007970188,0.0001373598,0.000141428,0.0001539099,0.00008367567,0.00003272018,0.0003272296,0.0002044579,0.00002258678],"category_scores_gemma":[0.00006255284,0.0001140451,0.00005563292,0.0006577181,0.0001555437,0.000008610339,0.0001208115,0.000264044,0.000005158476],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001356744,"about_ca_system_score_gemma":0.0002441969,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0031329,"about_ca_topic_score_gemma":0.0004494913,"domain_scores_codex":[0.9983265,0.0002306743,0.0003348084,0.0003784517,0.0003882069,0.0003413895],"domain_scores_gemma":[0.9988454,0.00005212368,0.0001142339,0.0004054168,0.0005032716,0.00007953391],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0002045853,0.0001933003,0.009321212,0.00001809755,0.00001943043,4.352267e-7,0.0001281103,0.00007520212,0.9824744,0.0000148938,0.00004032491,0.00751003],"study_design_scores_gemma":[0.001085241,0.00007449503,0.1839355,0.00001978544,0.000005032707,0.000003413415,0.00005435661,0.00004876832,0.8144295,0.0001874334,0.00005446433,0.0001019482],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977521,0.0006460796,0.0002176363,0.0007040015,0.00004133102,0.0003679855,0.0001223117,0.000007613524,0.0001409748],"genre_scores_gemma":[0.9991045,0.0003878922,0.00008792372,0.00001375856,0.00009541875,0.00008730335,0.000150888,0.00002640272,0.00004593558],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1746143,"threshold_uncertainty_score":0.4736029,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03344022320087554,"score_gpt":0.3310073115982659,"score_spread":0.2975670883973904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}