{"id":"W2098203176","doi":"10.1186/bcr799","title":"Chemically induced DNA hypomethylation in breast carcinoma cells detected by the amplification of intermethylated sites","year":2004,"lang":"en","type":"article","venue":"Breast Cancer Research","topic":"Epigenetics and DNA Methylation","field":"Biochemistry, Genetics and Molecular Biology","cited_by":32,"is_retracted":false,"has_abstract":true,"ca_institutions":"London Health Sciences Centre; Western University","funders":"Canadian Institutes of Health Research; Canadian Breast Cancer Research Alliance","keywords":"DNA methylation; Biology; Methylation; Genome instability; Molecular biology; Illumina Methylation Assay; Epigenetics; Genetics; Cancer research; Gene; DNA; Gene expression; DNA damage","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001006693,0.0002030117,0.0001651364,0.0002994076,0.0001315836,0.0001318808,0.0001532068,0.0002039268,0.00126623],"category_scores_gemma":[0.000119757,0.0001319375,0.0001203951,0.000251858,0.0001444657,0.00006455489,0.0001409358,0.0003411049,0.0003496155],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001430623,"about_ca_system_score_gemma":0.0001285659,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0007438489,"about_ca_topic_score_gemma":0.001298911,"domain_scores_codex":[0.9998828,0.00001606262,0.000008281665,0.00002984174,0.00004668187,0.00001633571],"domain_scores_gemma":[0.9999107,0.0000202361,0.00002722543,0.00001319083,0.00001721425,0.00001156088],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00002461227,0.000005640468,0.0007595692,0.00001477617,0.000004441561,0.00001826867,0.00001421994,0.00001131214,0.9985298,0.000009204865,0.000006039088,0.000602201],"study_design_scores_gemma":[0.000003335223,0.0001577163,0.03417889,0.000002604154,0.00001584512,0.0002652403,0.00002982241,0.0002294586,0.9645357,0.00001654311,0.000562596,0.00000229786],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9928452,0.00123818,0.003962888,0.00003043805,0.00001046383,0.00003156897,0.0004940839,0.00006855555,0.001318613],"genre_scores_gemma":[0.9921846,0.0007548785,0.004430636,0.00003161024,0.000004724152,0.00006277725,0.0009000653,0.00001090909,0.00161987],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00126623,"threshold_uncertainty_score":0.004235983,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.03344022320087554,"score_gpt":0.3310073115982659,"score_spread":0.2975670883973904,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}