{"id":"W2098216679","doi":"10.1016/j.tibs.2010.09.002","title":"Living without 30nm chromatin fibers","year":2010,"lang":"en","type":"article","venue":"Trends in Biochemical Sciences","topic":"Genomics and Chromatin Dynamics","field":"Biochemistry, Genetics and Molecular Biology","cited_by":189,"is_retracted":false,"has_abstract":false,"ca_institutions":"Hospital for Sick Children","funders":"Canadian Institutes of Health Research; Natural Sciences and Engineering Research Council of Canada; Canada Research Chairs","keywords":"Chromatin; ChIA-PET; Scaffold/matrix attachment region; Nucleosome; Genome; Cell biology; Biology; Computational biology; Genomic organization; Bivalent chromatin; Chromatin remodeling; DNA; Genetics; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003377559,0.000132245,0.0001132976,0.00007887821,0.0000874613,0.00004767061,0.0004316781,0.0001542011,0.0001411056],"category_scores_gemma":[0.00007899467,0.0001139712,0.00005763903,0.0002896427,0.0003948756,0.000004261215,0.000174462,0.0001453719,0.000008586841],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000009361686,"about_ca_system_score_gemma":0.00003998376,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003640009,"about_ca_topic_score_gemma":0.0001906646,"domain_scores_codex":[0.9989306,0.00001839369,0.0001885236,0.0004009008,0.000150693,0.0003108369],"domain_scores_gemma":[0.9995883,0.00001785593,0.00006093181,0.0002319056,0.00001603472,0.00008495143],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000002934701,0.00003953654,0.01827835,0.000003172906,0.000003389305,5.289584e-7,0.00004509825,0.0000160353,0.9775024,0.0001453188,0.0006688319,0.003294422],"study_design_scores_gemma":[0.0008216296,0.0004942933,0.1337978,0.00007691514,0.00001910052,0.00007970914,0.0003496929,0.009570782,0.8421569,0.001009015,0.01037608,0.001248074],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9895431,0.00008178047,0.00002666204,0.0001552693,0.0001779879,0.00003333885,0.000005564173,0.00001316968,0.009963097],"genre_scores_gemma":[0.9927942,0.00001640745,0.00644053,0.0001018922,0.000135232,0.000008010647,0.00002017454,0.000009023438,0.0004745191],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1353455,"threshold_uncertainty_score":0.464761,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.00943610750622595,"score_gpt":0.2742902402159649,"score_spread":0.2648541327097389,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}