{"id":"W2098230963","doi":"10.1056/nejmoa0902604","title":"Genetic Variants Associated with Lp(a) Lipoprotein Level and Coronary Disease","year":2009,"lang":"en","type":"article","venue":"New England Journal of Medicine","topic":"Lipoproteins and Cardiovascular Health","field":"Medicine","cited_by":1646,"is_retracted":false,"has_abstract":true,"ca_institutions":"Thrombosis and Atherosclerosis Research Institute","funders":"British Heart Foundation; Wellcome Trust","keywords":"Lipoprotein(a); Medicine; Coronary artery disease; Lipoprotein; Risk factor; Disease; Internal medicine; Genetic variants; Atherosclerotic cardiovascular disease; Cardiology; Genetics; Cholesterol; Gene; Genotype; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0007110985,0.0006116839,0.0004258221,0.0007862962,0.0003041043,0.000430639,0.0004451711,0.0008494176,0.002243771],"category_scores_gemma":[0.0027228,0.0002123596,0.0003997594,0.001228955,0.0005635467,0.0001124849,0.0002735998,0.0005034023,0.0003233323],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0002498938,"about_ca_system_score_gemma":0.0002588266,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002573141,"about_ca_topic_score_gemma":0.00163484,"domain_scores_codex":[0.9993641,0.0001354597,0.00006170869,0.0002614138,0.0001089926,0.00006837203],"domain_scores_gemma":[0.9973459,0.001303668,0.000786831,0.0001140176,0.0001784096,0.0002712065],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001912648,0.0001574513,0.9451546,0.0001191584,0.001028616,0.001712132,0.0001762547,0.0009427837,0.04164084,0.0002558269,0.0004686014,0.006431188],"study_design_scores_gemma":[0.0001076999,0.0002675766,0.9919909,0.00002468403,0.0004351642,0.002266239,0.00004349743,0.0009176877,0.00299798,0.0003086356,0.0006213026,0.00001864183],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9974123,0.0007772784,0.0008221489,0.0001291459,0.00001719993,0.00001294889,0.0005601075,0.00002326186,0.0002457002],"genre_scores_gemma":[0.9978408,0.0002453355,0.001144896,0.00006522764,0.00003788351,0.00001697574,0.0004405283,0.000009706871,0.0001987723],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002573141,"threshold_uncertainty_score":0.007506132,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.02224901186022214,"score_gpt":0.2553915572722287,"score_spread":0.2331425454120065,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}