{"id":"W2098339028","doi":"10.1186/1742-4690-6-100","title":"TRIM5α and TRIMCyp form apparent hexamers and their multimeric state is not affected by exposure to restriction-sensitive viruses or by treatment with pharmacological inhibitors","year":2009,"lang":"en","type":"article","venue":"Retrovirology","topic":"HIV Research and Treatment","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":true,"ca_institutions":"Université du Québec à Trois-Rivières","funders":"Canadian Institutes of Health Research; Canada Research Chairs","keywords":"Capsid; Cytoplasm; Cell biology; Chemistry; HEK 293 cells; Biology; Virology; Genetics; Virus; Cell culture","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00009331699,0.0003736465,0.0005359517,0.0001548063,0.0002443671,0.00002025216,0.00007212718,0.0002300774,0.00009630738],"category_scores_gemma":[0.00003669839,0.0002119841,0.00005267397,0.0002166415,0.000318608,0.00006846813,0.00004101179,0.0002463962,0.00007274404],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001529619,"about_ca_system_score_gemma":0.00007027361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000348368,"about_ca_topic_score_gemma":0.00004585086,"domain_scores_codex":[0.9981107,0.0003433056,0.0002475425,0.0006107101,0.00005158315,0.0006361608],"domain_scores_gemma":[0.999151,0.0003866715,0.00009319228,0.0001579316,0.0000446375,0.0001665612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.009803563,0.0011904,0.003899222,0.000004817071,0.0007735795,0.00008335119,0.001085719,0.000001395791,0.8691779,0.000001910818,0.01443931,0.09953882],"study_design_scores_gemma":[0.02090232,0.08270362,0.03442232,0.00001593401,0.0002278946,0.000274331,0.0005270936,0.000009045239,0.8153338,0.0000117129,0.04503542,0.0005365558],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9947852,0.002011944,0.00009493258,0.001116074,0.00007083509,0.0009871182,0.0007913561,0.00007817627,0.00006433894],"genre_scores_gemma":[0.9949529,0.002568867,0.00006371648,0.001268398,0.00001742626,0.0001098224,0.000182189,0.00001637208,0.0008203461],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.09900226,"threshold_uncertainty_score":0.864446,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0160466610976412,"score_gpt":0.2709388101276654,"score_spread":0.2548921490300242,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}