{"id":"W2098343450","doi":"10.1155/2013/634317","title":"Development of a <i>pyrG</i> Mutant of <i>Aspergillus oryzae</i> Strain S1 as a Host for the Production of Heterologous Proteins","year":2013,"lang":"en","type":"article","venue":"The Scientific World JOURNAL","topic":"Fungal and yeast genetics research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":25,"is_retracted":false,"has_abstract":true,"ca_institutions":"Concordia University","funders":"Ministério da Ciência, Tecnologia e Inovação; Natural Sciences and Engineering Research Council of Canada; Kementerian Sains, Teknologi dan Inovasi","keywords":"Auxotrophy; Aspergillus oryzae; Heterologous; Plasmid; Biology; Mutant; Gene; Aspergillus nidulans; Strain (injury); Mutagenesis; Genetics; Biochemistry; Enzyme","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.001354606,0.00009890742,0.0001358037,0.0000800167,0.0003233094,0.00004755597,0.0004880676,0.00003536897,0.00007737085],"category_scores_gemma":[0.0001614207,0.00005217552,0.0001143003,0.0002669322,0.0005349395,0.000005568223,0.0001330907,0.0001321897,0.000007655563],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00001047387,"about_ca_system_score_gemma":0.0003190794,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.000009788595,"about_ca_topic_score_gemma":0.00008949736,"domain_scores_codex":[0.9986825,0.00007733958,0.0004061181,0.0001951854,0.000391461,0.0002473819],"domain_scores_gemma":[0.9987358,0.0000279161,0.000275775,0.0003654076,0.0005406231,0.00005445871],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.000115785,0.00008909857,0.00003259899,0.00003536062,0.00007170192,2.10056e-7,0.0004402651,0.0001209814,0.9890296,0.00003261348,0.001792295,0.00823946],"study_design_scores_gemma":[0.0002358988,0.0001943472,0.0003239796,0.00003997293,0.00001522857,0.00004232593,0.0003108944,0.00006242103,0.9798777,0.0001915035,0.01864417,0.00006163545],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9965841,0.0005601209,0.0004219367,0.0009490228,0.0004758746,0.0008019146,0.00002657343,0.000001713186,0.0001787608],"genre_scores_gemma":[0.9939869,0.00003108728,0.001969697,0.00002724434,0.0001303896,0.00004908718,0.000009682733,0.00001031005,0.003785568],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.01685187,"threshold_uncertainty_score":0.2486667,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01876239416455022,"score_gpt":0.26226995650028,"score_spread":0.2435075623357298,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}