{"id":"W2098431893","doi":"10.1002/anie.201102486","title":"Artificially Induced Protein–Membrane Anchorage with Cholesterol‐Based Recognition Agents as a New Therapeutic Concept","year":2011,"lang":"en","type":"article","venue":"Angewandte Chemie International Edition","topic":"Monoclonal and Polyclonal Antibodies Research","field":"Medicine","cited_by":18,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; Ontario Institute for Cancer Research; University of Toronto","funders":"National Cancer Institute; Canadian Institutes of Health Research","keywords":"Liposome; Cell biology; Membrane; Motility; In vitro; Chemistry; Vesicle; Membrane protein; Biochemistry; Biology","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002285228,0.0002935298,0.0002130443,0.0001878049,0.0001444869,0.0003794685,0.0003200877,0.0004678025,0.0004651377],"category_scores_gemma":[0.0001727683,0.0001598697,0.0002451964,0.0001204847,0.0003798532,0.0003026986,0.000260239,0.000673093,0.0002294406],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003555899,"about_ca_system_score_gemma":0.0002501579,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002707576,"about_ca_topic_score_gemma":0.0002902937,"domain_scores_codex":[0.9998834,0.00002922909,0.000007781637,0.00002174538,0.00003216752,0.00002562863],"domain_scores_gemma":[0.9999343,0.0000162273,0.00001771917,0.00001146045,0.000008629928,0.00001163453],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007758167,0.00004308503,0.00004472352,0.00004452979,0.000005885002,0.00008429013,0.00002103838,0.0001430739,0.9954716,0.001260195,0.00006528024,0.002738718],"study_design_scores_gemma":[0.00002769007,0.0001842363,0.0001093414,0.00000276721,0.00001346565,0.0001365073,0.000004883054,0.0005670101,0.9954361,0.0001017787,0.003409061,0.000007200098],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9323976,0.005570771,0.05517475,0.001017363,0.0002452516,0.0002213887,0.0001799583,0.0004378139,0.004755093],"genre_scores_gemma":[0.9809452,0.001647667,0.01513821,0.0001664883,0.00002513784,0.00008073005,0.00009612656,0.00002463231,0.001875766],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0004678025,"threshold_uncertainty_score":0.002579987,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.1027900686073886,"score_gpt":0.321689512647998,"score_spread":0.2188994440406094,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}