{"id":"W2098474651","doi":"10.1128/iai.68.1.54-63.2000","title":"Archaeosome Vaccine Adjuvants Induce Strong Humoral, Cell-Mediated, and Memory Responses: Comparison to Conventional Liposomes and Alum","year":2000,"lang":"en","type":"article","venue":"Infection and Immunity","topic":"Immunotherapy and Immune Responses","field":"Immunology and Microbiology","cited_by":157,"is_retracted":false,"has_abstract":true,"ca_institutions":"Institute for Biological Sciences","funders":"","keywords":"Adjuvant; Antigen; Biology; Immune system; Ovalbumin; Alum; Antibody; Liposome; Bovine serum albumin; Molecular biology; Immunology; Biochemistry; Chemistry","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":[],"category_scores_codex":[0.0004710334,0.0002526979,0.0003872295,0.0002606411,0.0006438834,0.00005246539,0.00009389131,0.0002282902,0.001456848],"category_scores_gemma":[0.0000974457,0.0002409622,0.00005122197,0.0001720198,0.0002761249,0.0002509777,0.00011442,0.0005229262,0.0001658409],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00002730105,"about_ca_system_score_gemma":0.00004929148,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001094483,"about_ca_topic_score_gemma":0.00005648026,"domain_scores_codex":[0.9982041,0.0007456597,0.0003799777,0.0002905351,0.000048112,0.000331682],"domain_scores_gemma":[0.9991637,0.0003675162,0.00009780315,0.0002510635,0.000060323,0.00005962806],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"observational","study_design_scores_codex":[0.008726027,0.0008452497,0.06256826,0.0001020112,0.000414762,0.000007832454,0.004980883,0.00000990825,0.7722763,0.0001169072,0.001836901,0.1481149],"study_design_scores_gemma":[0.005267375,0.001471753,0.8390157,0.0001000548,0.00005469419,0.0003521918,0.0009887666,0.0000167494,0.0622256,0.00005653725,0.09000342,0.0004471832],"study_design_candidate":"observational","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9853685,0.0129909,0.0000187672,0.0003312043,0.0003518215,0.0003257551,0.00003809819,0.00008425855,0.000490636],"genre_scores_gemma":[0.9911838,0.004077701,0.00002864493,0.0002766439,0.0000255862,0.00002772306,0.00008258467,0.000019671,0.004277607],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7764474,"threshold_uncertainty_score":0.9994559,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0192349444326061,"score_gpt":0.2774875019069037,"score_spread":0.2582525574742976,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}