{"id":"W2098557986","doi":"10.1093/infdis/jit247","title":"Bacillus anthracis Cell Wall Peptidoglycan but Not Lethal or Edema Toxins Produces Changes Consistent With Disseminated Intravascular Coagulation in a Rat Model","year":2013,"lang":"en","type":"article","venue":"The Journal of Infectious Diseases","topic":"Bacillus and Francisella bacterial research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":31,"is_retracted":false,"has_abstract":true,"ca_institutions":"National Research Council Canada","funders":"","keywords":"Bacillus anthracis; Disseminated intravascular coagulation; Fibrinogen; Anthrax toxin; Pathogenesis; Peptidoglycan; Immunology; Toxin; Coagulation; Tissue factor; Thromboplastin; Medicine; Partial thromboplastin time; Microbiology; Pharmacology; Internal medicine; Biology; Biochemistry; Cell wall","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003331261,0.0001983217,0.0002725208,0.00009882681,0.0001222097,0.00007231948,0.0002072805,0.00009837703,0.00007807466],"category_scores_gemma":[0.0001887848,0.0001104002,0.00009114676,0.0001495811,0.0001906264,0.00002225072,0.0000654023,0.0001723434,0.000005056667],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0000501172,"about_ca_system_score_gemma":0.0002399414,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001652143,"about_ca_topic_score_gemma":0.0004885784,"domain_scores_codex":[0.9987062,0.00019321,0.0003062279,0.0001902005,0.0003071538,0.0002970755],"domain_scores_gemma":[0.9988372,0.00005661426,0.0002364245,0.0002671079,0.0004362058,0.0001664835],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.002019946,0.0004507029,0.003788469,0.00009248682,0.000112908,0.00002701065,0.0003806122,0.003844303,0.9841549,0.000003191758,0.0007671265,0.004358355],"study_design_scores_gemma":[0.006047206,0.006030203,0.02746968,0.0002874335,0.0003888858,0.0007200773,0.001238323,0.005932766,0.9498134,0.0001146227,0.001158936,0.0007985112],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9977256,0.0008857216,0.0003129152,0.0004063572,0.00008705176,0.0004391717,0.00002165514,0.000007410497,0.0001140977],"genre_scores_gemma":[0.9981018,0.001073328,0.00003983543,0.0001181097,0.0001916468,0.00002628863,0.00001803017,0.00002441243,0.0004065797],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03434153,"threshold_uncertainty_score":0.4501989,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01224893948923442,"score_gpt":0.2422387710012266,"score_spread":0.2299898315119922,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}