{"id":"W2098563549","doi":"10.1111/mmi.13059","title":"Catecholate siderophore esterases Fes, <scp>IroD</scp> and <scp>IroE</scp> are required for salmochelins secretion following utilization, but only <scp>IroD</scp> contributes to virulence of extra‐intestinal pathogenic <scp><i>E</i></scp><i>scherichia coli</i>","year":2015,"lang":"en","type":"article","venue":"Molecular Microbiology","topic":"Bacterial Genetics and Biotechnology","field":"Biochemistry, Genetics and Molecular Biology","cited_by":36,"is_retracted":false,"has_abstract":true,"ca_institutions":"Armand Frappier Museum; Institut National de la Recherche Scientifique","funders":"Natural Sciences and Engineering Research Council of Canada; Armand-Frappier Foundation","keywords":"Enterobactin; Virulence; Siderophore; Biology; Mutant; Secretion; Microbiology; Escherichia coli; Salmonella enterica; Aerobactin; Virulence factor; Pathogenic Escherichia coli; Colicin; Intracellular; Biochemistry; Enterobacteriaceae; Gene","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["metaepi_narrow","research_integrity"],"consensus_categories":[],"category_scores_codex":[0.0009354426,0.001116727,0.001341296,0.0003704915,0.0003419913,0.0001646472,0.001057912,0.001898686,0.000001433557],"category_scores_gemma":[0.006941483,0.001164873,0.0005104177,0.0007076999,0.0006491917,0.00003703326,0.000868633,0.0005419895,0.00002336152],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001189435,"about_ca_system_score_gemma":0.0005693936,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00007699494,"about_ca_topic_score_gemma":0.000159059,"domain_scores_codex":[0.9940765,0.0005212894,0.001412542,0.002080547,0.0002462596,0.001662873],"domain_scores_gemma":[0.9956493,0.0005365324,0.0009707642,0.001251148,0.001039457,0.0005527559],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00004238636,0.0002630817,0.003336244,0.0001646389,0.0003939514,0.00007654026,0.0002798556,0.00007884406,0.9897407,0.0001444174,0.00496667,0.0005127098],"study_design_scores_gemma":[0.00269891,0.001899803,0.00239364,0.0001896914,0.0003619922,0.0004027194,0.001108857,0.00007686505,0.8800306,0.0004293679,0.1102269,0.0001806406],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9633061,0.01512805,0.01727134,0.0002025991,0.0009015992,0.001830033,0.001102149,0.00014872,0.0001094646],"genre_scores_gemma":[0.9862383,0.001117915,0.006813008,0.001659114,0.0002819268,0.0002431359,0.002600579,0.0002210883,0.0008249315],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1097101,"threshold_uncertainty_score":0.999397,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01885082333676118,"score_gpt":0.243774487696489,"score_spread":0.2249236643597278,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}