{"id":"W2098574165","doi":"10.1016/s0014-5793(01)02663-1","title":"Mice lacking histidine decarboxylase exhibit abnormal mast cells","year":2001,"lang":"en","type":"article","venue":"FEBS Letters","topic":"Mast cells and histamine","field":"Immunology and Microbiology","cited_by":397,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto; Lunenfeld-Tanenbaum Research Institute; Mount Sinai Hospital","funders":"Kanae Foundation for the Promotion of Medical Science; Mochida Memorial Foundation for Medical and Pharmaceutical Research","keywords":"Histidine decarboxylase; Histamine; Histidine; Proteases; Mast cell; Chemistry; Histamine N-methyltransferase; Histamine H4 receptor; Biology; Biochemistry; Cell biology; Molecular biology; Immunology; Enzyme; Histamine H2 receptor; Pharmacology; Receptor","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":["insufficient_payload"],"consensus_categories":["insufficient_payload"],"category_scores_codex":[0.0001368395,0.0002150552,0.0002413465,0.0001132593,0.0001877442,0.00002330149,0.000224838,0.0001388532,0.003527105],"category_scores_gemma":[0.00001172912,0.0002087926,0.0001017635,0.0001309482,0.0001568505,0.00008657103,0.00007910647,0.0002837202,0.002102996],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006021533,"about_ca_system_score_gemma":0.00001653618,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002399221,"about_ca_topic_score_gemma":0.00008995905,"domain_scores_codex":[0.9987646,0.00007355687,0.0002653352,0.0003309516,0.0000426114,0.0005229083],"domain_scores_gemma":[0.9994897,0.00006522323,0.0001019729,0.000275093,0.00002804333,0.00004001612],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"not_applicable","study_design_scores_codex":[0.0001096586,0.00006593367,0.001624459,0.00001716775,0.0000465358,0.0001484828,0.0001775261,0.00003994978,0.9282846,0.0001259563,0.06793002,0.001429738],"study_design_scores_gemma":[0.001353783,0.0000716061,0.002052395,0.00002603328,0.00003917438,0.0001863943,0.00005845872,0.00001375307,0.1371309,0.000005428834,0.8587226,0.0003394236],"study_design_candidate":"bench_or_experimental","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.984107,0.0009631547,0.000637845,0.003015826,0.00143273,0.0001515037,0.00002629693,0.0001231184,0.009542589],"genre_scores_gemma":[0.9811235,0.00006915357,0.0002209954,0.00472023,0.0001883813,0.00001019711,0.0001180993,0.00003063245,0.01351878],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.7911537,"threshold_uncertainty_score":0.998674,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.009288454777363033,"score_gpt":0.1981538719377585,"score_spread":0.1888654171603955,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}