{"id":"W2098589170","doi":"10.1038/onc.2009.515","title":"Formin-like 2 drives amoeboid invasive cell motility downstream of RhoC","year":2010,"lang":"en","type":"article","venue":"Oncogene","topic":"Cellular Mechanics and Interactions","field":"Biochemistry, Genetics and Molecular Biology","cited_by":144,"is_retracted":false,"has_abstract":false,"ca_institutions":"University of Ottawa","funders":"","keywords":"RhoC; Formins; RHOA; Biology; Cell biology; GTPase; Actin; Effector; Actin cytoskeleton; Motility; MDia1; RHOB; Cell migration; Cytoskeleton; Cell; Signal transduction; Genetics","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002472454,0.0003559911,0.0002289887,0.0004069071,0.0004298501,0.0006545326,0.0004080741,0.0005837582,0.001868761],"category_scores_gemma":[0.0001867502,0.0003275831,0.0003252677,0.0002012945,0.0004554079,0.0003078654,0.000491867,0.001284095,0.000816645],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.001003038,"about_ca_system_score_gemma":0.000383027,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001042467,"about_ca_topic_score_gemma":0.002755812,"domain_scores_codex":[0.9996628,0.00004578902,0.00003109064,0.00005843918,0.0001111272,0.00009073206],"domain_scores_gemma":[0.9997428,0.00006131,0.00005320866,0.00004261465,0.00001585299,0.00008429064],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.00007112677,0.00002541389,0.0000640595,0.0000104811,0.000001889164,0.00003627226,0.00001393394,0.00003837089,0.9990551,0.0003349759,0.00005712848,0.0002912523],"study_design_scores_gemma":[0.00002848622,0.00004989023,0.00241818,0.000002972907,0.000005495102,0.0001412163,0.00005840624,0.002857794,0.9911862,0.00010221,0.00314436,0.000004812205],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9914904,0.0002730945,0.003507799,0.0003167012,0.00007243714,0.00003679232,0.0004090344,0.0001586647,0.003734907],"genre_scores_gemma":[0.9910314,0.0001269405,0.002361111,0.0001014353,0.00001513383,0.00003273439,0.0005319286,0.0000812468,0.005718082],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001868761,"threshold_uncertainty_score":0.007277608,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.004556187248277722,"score_gpt":0.2222102308152965,"score_spread":0.2176540435670187,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}