{"id":"W2098797664","doi":"10.1016/j.bbamcr.2006.08.003","title":"Differential regulation of lipopolysaccharide and Gram-positive bacteria induced cytokine and chemokine production in splenocytes by Gαi proteins","year":2006,"lang":"en","type":"article","venue":"Biochimica et Biophysica Acta (BBA) - Molecular Cell Research","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":15,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"National Institute of Diabetes and Digestive and Kidney Diseases; National Institute of General Medical Sciences; National Institutes of Health","keywords":"Splenocyte; Chemokine; Cytokine; Lipopolysaccharide; TLR4; TLR2; CXCL10; Chemistry; Molecular biology; Biology; Immunology; Spleen; Inflammation","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002340155,0.0006103691,0.0003569204,0.0003661346,0.0001897878,0.0003409544,0.0002201523,0.0003405136,0.00108895],"category_scores_gemma":[0.0002232594,0.0002173238,0.0005272866,0.0002819284,0.0004283391,0.0002846479,0.0002683129,0.001122517,0.0004989899],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0003265167,"about_ca_system_score_gemma":0.0002230824,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003114746,"about_ca_topic_score_gemma":0.0003768877,"domain_scores_codex":[0.999715,0.00005670653,0.00002043817,0.00003819694,0.00003554283,0.0001341943],"domain_scores_gemma":[0.9997582,0.00006147195,0.00004222448,0.00004208245,0.00002256751,0.00007358829],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0008899776,0.0000446746,0.0001471025,0.00002036937,0.000003402645,0.00003423439,0.0000133542,0.00002686835,0.998386,0.00004884443,0.00002480103,0.0003602145],"study_design_scores_gemma":[0.00007188243,0.0007624488,0.01178588,0.000008070509,0.00002292462,0.0001032786,0.0000574697,0.0004498341,0.9860779,0.00008691778,0.0005676991,0.000005716428],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9963284,0.0009884055,0.001115071,0.0001731148,0.00004970406,0.00002866397,0.0004456174,0.00005375238,0.0008173324],"genre_scores_gemma":[0.9947816,0.0007310103,0.001390514,0.0001436083,0.00004115505,0.00009058313,0.00112249,0.00002547183,0.001673586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.00108895,"threshold_uncertainty_score":0.003642917,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01195431387603785,"score_gpt":0.2587415444299618,"score_spread":0.2467872305539239,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}