{"id":"W2098836416","doi":"10.1002/ana.24163","title":"Pathologic heterogeneity persists in early active multiple sclerosis lesions","year":2014,"lang":"en","type":"article","venue":"Annals of Neurology","topic":"Multiple Sclerosis Research Studies","field":"Medicine","cited_by":136,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Saskatchewan; Cameco (Canada)","funders":"National Institute of Neurological Disorders and Stroke","keywords":"Multiple sclerosis; Autopsy; Biopsy; Pathological; Medicine; Pathology; Demyelinating disease; Disease; Immunology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0004016903,0.0001599398,0.0005078189,0.0002542452,0.00006921593,0.000004748452,0.0001648684,0.0001502187,0.00002614012],"category_scores_gemma":[0.002432707,0.0001363232,0.0001667008,0.0002301022,0.0003367429,0.00006207756,0.0001967341,0.0003639057,0.00003401437],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000007585666,"about_ca_system_score_gemma":0.00002475002,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0002394056,"about_ca_topic_score_gemma":0.0002188727,"domain_scores_codex":[0.9981381,0.0004186119,0.0003035393,0.0004084085,0.0002469676,0.0004843292],"domain_scores_gemma":[0.9985157,0.0006427232,0.000103594,0.0003892443,0.000203865,0.0001449144],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"observational","study_design_gemma":"observational","study_design_scores_codex":[0.001676957,0.0007042599,0.8310815,0.00006693335,0.00008300828,0.00007177211,0.0009017313,0.00004969752,0.1353202,0.0000358972,0.000825709,0.02918229],"study_design_scores_gemma":[0.00122916,0.00185025,0.9759483,0.00002757356,0.000009675951,0.00001213028,0.00003163323,0.0003655474,0.01981835,0.00004981654,0.0005723009,0.00008524061],"study_design_candidate":"observational","study_design_consensus":"observational","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9925371,0.0001090124,0.00001719292,0.006165664,0.0000632762,0.0003212007,0.00002217569,0.00003309799,0.0007312538],"genre_scores_gemma":[0.9966421,0.0007015899,0.0001038905,0.002413438,0.00005528044,0.00004477592,0.000006040823,0.000016807,0.00001611713],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1448668,"threshold_uncertainty_score":0.5559099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2465430350193815,"score_gpt":0.3702981419486182,"score_spread":0.1237551069292367,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}