{"id":"W2098912985","doi":"10.1128/jvi.79.9.5594-5605.2005","title":"Recruitment of CBP/p300, TATA-Binding Protein, and S8 to Distinct Regions at the N Terminus of Adenovirus E1A","year":2005,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Virus-based gene therapy research","field":"Biochemistry, Genetics and Molecular Biology","cited_by":42,"is_retracted":false,"has_abstract":true,"ca_institutions":"Western University","funders":"Cancer Research UK","keywords":"Biology; TATA-binding protein; DNA-binding protein; Binding site; Mutagenesis; Mutant; Plasma protein binding; Point mutation; RNA-binding protein; TATA-Box Binding Protein; Mutation; Cell biology; Molecular biology; Gene; Transcription factor; Genetics; RNA","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0002063847,0.0002670807,0.0001813513,0.0001627159,0.0001567919,0.000316205,0.000249724,0.0002166541,0.0007152972],"category_scores_gemma":[0.0001772702,0.0001959271,0.0002992746,0.00009536489,0.0003490384,0.0001586225,0.0002472765,0.0004000329,0.0003837269],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006683609,"about_ca_system_score_gemma":0.0005425127,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.001535314,"about_ca_topic_score_gemma":0.002183332,"domain_scores_codex":[0.9998306,0.0000266424,0.00002038319,0.00004036414,0.00004213329,0.00003987997],"domain_scores_gemma":[0.9998492,0.00002375765,0.00003798931,0.00002007632,0.00001400382,0.00005496713],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001010516,0.00001773119,0.0002060865,0.00001338837,0.000002462187,0.00001996051,0.0000116312,0.00005028164,0.9990607,0.00007984477,0.000009460379,0.0004274983],"study_design_scores_gemma":[0.00002406314,0.0001436205,0.00496772,0.000006489773,0.00001225817,0.0001552669,0.00003636548,0.001808556,0.9914206,0.00004475659,0.00137477,0.000005457843],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9982631,0.0003478682,0.0008666192,0.00002851231,0.000006256911,0.00001111811,0.00004745198,0.00001832068,0.0004107557],"genre_scores_gemma":[0.995455,0.0001885501,0.002501856,0.00002849411,0.000002669369,0.00002408417,0.0002530489,0.0000119963,0.001534366],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001535314,"threshold_uncertainty_score":0.004849315,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.04633829668461623,"score_gpt":0.3410337032137263,"score_spread":0.2946954065291101,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}