{"id":"W2099075331","doi":"10.1016/j.steroids.2003.09.005","title":"Synthesis and biological properties of 7α-cyano derivatives of the (17α,20E/Z)-[125I]iodovinyl- and 16α-[125I]iodo-estradiols","year":2003,"lang":"en","type":"article","venue":"Steroids","topic":"Estrogen and related hormone effects","field":"Biochemistry, Genetics and Molecular Biology","cited_by":12,"is_retracted":false,"has_abstract":false,"ca_institutions":"Université de Sherbrooke","funders":"Canadian Institutes of Health Research","keywords":"Triethylborane; Chemistry; Potency; Estrogen receptor; Receptor; Stereochemistry; Stereospecificity; Estrogen; Catalysis; Medicinal chemistry; In vitro; Internal medicine; Biochemistry; Biology; Endocrinology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0003823969,0.000417624,0.0003542273,0.0003208249,0.0003474606,0.0003194486,0.0006724589,0.0003205179,0.002398542],"category_scores_gemma":[0.0004836653,0.0002484399,0.0002546587,0.0002815816,0.0003283914,0.0002661245,0.0002391547,0.0004784128,0.0009137906],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0006571534,"about_ca_system_score_gemma":0.0004593738,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.002423991,"about_ca_topic_score_gemma":0.001547386,"domain_scores_codex":[0.9997767,0.00004986234,0.00001580076,0.00003743167,0.00005435255,0.00006581088],"domain_scores_gemma":[0.9996151,0.00007265725,0.00006090399,0.000043985,0.00009046551,0.0001169349],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0004958194,0.00006503869,0.0002478135,0.00006545185,0.0000160329,0.000193209,0.00007935551,0.0004227285,0.993727,0.0007941672,0.0001473753,0.003746045],"study_design_scores_gemma":[0.00002650125,0.000282159,0.0009840268,0.000004842141,0.0000141847,0.0001390228,0.0000159564,0.0002809709,0.9935075,0.00006138873,0.004674265,0.000009172396],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.973892,0.00650533,0.007043454,0.0002386296,0.0001015344,0.0000895402,0.0009257281,0.0001119558,0.01109178],"genre_scores_gemma":[0.9764022,0.003074421,0.004767547,0.0001142802,0.00004946815,0.00007176121,0.002441473,0.00007295916,0.01300586],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.002423991,"threshold_uncertainty_score":0.008023977,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01431342150764199,"score_gpt":0.2058526549512487,"score_spread":0.1915392334436067,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}