{"id":"W2099110757","doi":"10.1371/journal.pgen.0020196","title":"Functional Identification of Api5 as a Suppressor of E2F-Dependent Apoptosis In Vivo","year":2006,"lang":"en","type":"article","venue":"PLoS Genetics","topic":"Cancer-related Molecular Pathways","field":"Medicine","cited_by":126,"is_retracted":false,"has_abstract":true,"ca_institutions":"","funders":"National Institute of General Medical Sciences; National Cancer Institute; Canadian Institutes of Health Research; National Institutes of Health","keywords":"E2F; Biology; Apoptosis; Inhibitor of apoptosis; Cell biology; Programmed cell death; Transcription factor; Caspase; Carcinogenesis; Intrinsic apoptosis; Cancer research; Cell cycle; Molecular biology; Genetics; Gene","routes":{"ca_aff":false,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":true},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001921927,0.0004301825,0.0001957906,0.0003665723,0.0002000831,0.0004021893,0.0003648828,0.0003184115,0.001297902],"category_scores_gemma":[0.0001437434,0.0001709649,0.0002751862,0.0001490362,0.000191145,0.0001776572,0.0002334479,0.000526904,0.0005181647],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0005510875,"about_ca_system_score_gemma":0.0002143888,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0006482438,"about_ca_topic_score_gemma":0.000801642,"domain_scores_codex":[0.9998261,0.00002862037,0.00002451287,0.00003770884,0.00005155786,0.00003138816],"domain_scores_gemma":[0.9998003,0.00003906851,0.0000670779,0.00002642414,0.00001326515,0.00005393285],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0000740915,0.00002371071,0.0002216664,0.00001699127,0.000005624735,0.00005541851,0.000004301474,0.0000618717,0.9982489,0.0001480281,0.00002770039,0.001111672],"study_design_scores_gemma":[0.00002053816,0.0001811514,0.004810715,0.000003586648,0.00002160512,0.0004401062,0.00001341761,0.001356614,0.9902124,0.00004025981,0.002895338,0.000004197861],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9888516,0.002022215,0.006042578,0.0001233456,0.00002996769,0.0000383767,0.0007504119,0.0001539738,0.001987593],"genre_scores_gemma":[0.9936796,0.0005152239,0.002004182,0.00004327804,0.000005810268,0.0000258424,0.001303705,0.00002938841,0.002392959],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.001297902,"threshold_uncertainty_score":0.0043419,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.01605084524360574,"score_gpt":0.2354612783948885,"score_spread":0.2194104331512828,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}