{"id":"W2099226585","doi":"10.1128/jvi.01036-06","title":"Induction of Innate Immunity against Herpes Simplex Virus Type 2 Infection via Local Delivery of Toll-Like Receptor Ligands Correlates with Beta Interferon Production","year":2006,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":109,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; McMaster University Medical Centre","funders":"Canadian Institutes of Health Research","keywords":"Biology; Innate immune system; TLR2; Herpes simplex virus; TLR3; Interferon; Immunology; Virology; Tumor necrosis factor alpha; TLR9; TLR4; Alpha interferon; Interferon type I; Interferon gamma; Toll-like receptor; Cytokine; Virus; Inflammation; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0005634478,0.0001548753,0.0004444912,0.0003886286,0.00008793081,0.000004242613,0.0001112516,0.0003633058,0.00007318591],"category_scores_gemma":[0.00004720375,0.000123032,0.00009760221,0.0002404679,0.000353845,0.0003163498,0.00003874881,0.0004408032,0.00001865997],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00007508107,"about_ca_system_score_gemma":0.0001007488,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0003434504,"about_ca_topic_score_gemma":0.00009682502,"domain_scores_codex":[0.9984711,0.0003568074,0.0008117873,0.0001232608,0.00005926628,0.0001777427],"domain_scores_gemma":[0.998125,0.00007967321,0.001135468,0.0001684713,0.0004796692,0.00001173351],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.007841081,0.0002958396,0.00202286,0.00002920306,0.0002871047,0.000002215263,0.0002629838,0.001036206,0.9539302,0.00002637077,0.0005699219,0.03369603],"study_design_scores_gemma":[0.00125535,0.003731073,0.02616105,0.00008451652,0.0001184892,0.000341019,0.0001247616,0.00002614281,0.9629273,0.00007014314,0.005047343,0.0001127969],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9959583,0.001103833,0.00100321,0.0001536093,0.001596856,0.000119447,0.00000229751,0.0000131735,0.0000493191],"genre_scores_gemma":[0.9990662,0.0006011261,0.00003889158,0.00002281262,0.00009173591,0.000001808502,0.00005265676,0.00001379142,0.000110973],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.03358324,"threshold_uncertainty_score":0.5017099,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007189988796909921,"score_gpt":0.2127247014426892,"score_spread":0.2055347126457792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}