{"id":"W2099226585","doi":"10.1128/jvi.01036-06","title":"Induction of Innate Immunity against Herpes Simplex Virus Type 2 Infection via Local Delivery of Toll-Like Receptor Ligands Correlates with Beta Interferon Production","year":2006,"lang":"en","type":"article","venue":"Journal of Virology","topic":"Immune Response and Inflammation","field":"Immunology and Microbiology","cited_by":109,"is_retracted":false,"has_abstract":true,"ca_institutions":"Health Sciences Centre; McMaster University Medical Centre","funders":"Canadian Institutes of Health Research","keywords":"Biology; Innate immune system; TLR2; Herpes simplex virus; TLR3; Interferon; Immunology; Virology; Tumor necrosis factor alpha; TLR9; TLR4; Alpha interferon; Interferon type I; Interferon gamma; Toll-like receptor; Cytokine; Virus; Inflammation; Immune system","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001369828,0.0003386227,0.0001840383,0.0001256808,0.00005420841,0.0002780196,0.00009404137,0.0001673017,0.0008904079],"category_scores_gemma":[0.0001086438,0.0001005989,0.0001370565,0.00006851715,0.0001921582,0.0001741201,0.0001267786,0.0004791654,0.0003228358],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.0001458452,"about_ca_system_score_gemma":0.00009388967,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.0001031773,"about_ca_topic_score_gemma":0.0001340931,"domain_scores_codex":[0.9999011,0.00001730521,0.000009627711,0.00002498048,0.00002006408,0.00002701101],"domain_scores_gemma":[0.9998606,0.00002383967,0.00005153712,0.00001983695,0.0000110554,0.00003309722],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001098273,0.00001874799,0.000284219,0.00003050637,0.000002371301,0.00001855479,0.000004932343,0.00001675157,0.9984225,0.00001845825,0.00001441025,0.001058703],"study_design_scores_gemma":[0.00002363799,0.0009505667,0.01516524,0.00001620732,0.0000155622,0.000364794,0.00002750645,0.0004610412,0.9817709,0.00003850555,0.001162541,0.000003455842],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9931443,0.002581124,0.002739039,0.00005939186,0.00003523398,0.00002890352,0.0002167123,0.0001020922,0.001093072],"genre_scores_gemma":[0.9941337,0.001549299,0.002326756,0.00005766314,0.00002762247,0.00005421633,0.0004050241,0.00002297147,0.001422811],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.0008904079,"threshold_uncertainty_score":0.002978683,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.007189988796909921,"score_gpt":0.2127247014426892,"score_spread":0.2055347126457792,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}