{"id":"W2099260574","doi":"10.1093/humrep/15.2.440","title":"Fluorescence in-situ hybridization of sex chromosomes in spermatozoa and spare preimplantation embryos of a Klinefelter 46,XY/47,XXY male","year":2000,"lang":"en","type":"article","venue":"Human Reproduction","topic":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","field":"Biochemistry, Genetics and Molecular Biology","cited_by":60,"is_retracted":false,"has_abstract":true,"ca_institutions":"Royal Victoria Hospital","funders":"McGill University","keywords":"Biology; Fluorescence in situ hybridization; Intracytoplasmic sperm injection; Karyotype; Aneuploidy; Blastomere; Andrology; Klinefelter syndrome; Y chromosome; Chromosome; Embryo; Ploidy; Genetics; In vitro fertilisation; Embryogenesis; Endocrinology; Medicine","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.0001410026,0.000090974,0.0001529452,0.00006093395,0.00002555675,0.000007578455,0.00006104673,0.00006920019,0.0001072611],"category_scores_gemma":[0.00002504344,0.00009213491,0.00002904805,0.00008006192,0.00009568888,0.00001219639,0.00002240145,0.0000506863,0.000002054325],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.000006781123,"about_ca_system_score_gemma":0.00001632964,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00003433058,"about_ca_topic_score_gemma":0.00008204315,"domain_scores_codex":[0.9990484,0.00004776576,0.0003831524,0.0003165158,0.000102533,0.0001016085],"domain_scores_gemma":[0.9996008,0.000005274634,0.0001063685,0.0002098665,0.00005476707,0.00002292899],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"bench_or_experimental","study_design_gemma":"bench_or_experimental","study_design_scores_codex":[0.0001253543,0.0002242773,0.0620794,0.0002162413,0.00001201305,0.000005036397,0.0007024408,0.0003051458,0.9162229,0.00007307598,0.00007515421,0.0199589],"study_design_scores_gemma":[0.0006384414,0.0002499994,0.2606648,0.00007184944,0.000008388586,0.00006694356,0.0004730798,0.00004274469,0.7371417,0.0001462332,0.0003716486,0.0001242188],"study_design_candidate":"bench_or_experimental","study_design_consensus":"bench_or_experimental","genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.9979787,0.0002716996,0.000008010185,0.00005121471,0.00003581599,0.0001651224,0.000005943395,0.000004788697,0.001478688],"genre_scores_gemma":[0.9974457,0.00052125,0.0001227823,0.00001807481,0.0001062545,0.000009804016,0.0001011763,0.0000074298,0.001667541],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.1985854,"threshold_uncertainty_score":0.3757152,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.0123807048326777,"score_gpt":0.2612812392921356,"score_spread":0.248900534459458,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}