{"id":"W2099329054","doi":"10.1146/annurev-genom-082509-141730","title":"Genetic Interaction Networks: Toward an Understanding of Heritability","year":2013,"lang":"en","type":"review","venue":"Annual Review of Genomics and Human Genetics","topic":"Bioinformatics and Genomic Networks","field":"Biochemistry, Genetics and Molecular Biology","cited_by":120,"is_retracted":false,"has_abstract":true,"ca_institutions":"University of Toronto","funders":"National Human Genome Research Institute; Canadian Institutes of Health Research","keywords":"Biology; Pairwise comparison; Computational biology; Missing heritability problem; Saccharomyces cerevisiae; Set (abstract data type); Genetics; Evolutionary biology; Computer science; Gene; Artificial intelligence; Genotype; Genetic variants","routes":{"ca_aff":true,"ca_fund":true,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"metacan-v3-hybrid-931329e0061c","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.002169203,0.001272147,0.002142408,0.003444958,0.0003576867,0.002238703,0.002038036,0.002073827,0.003289699],"category_scores_gemma":[0.004153223,0.0006383534,0.0008279588,0.002521871,0.002687749,0.003421452,0.001306401,0.003003493,0.001287526],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.002282616,"about_ca_system_score_gemma":0.00200361,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.004073785,"about_ca_topic_score_gemma":0.002503317,"domain_scores_codex":[0.9994134,0.0002135559,0.00004201742,0.0001363966,0.0001615179,0.00003309352],"domain_scores_gemma":[0.9975716,0.001798723,0.0001670146,0.000110729,0.0002734549,0.00007857961],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"not_applicable","study_design_scores_codex":[0.00005339343,0.00004429292,0.002079502,0.006520605,0.0003726269,0.0004474484,0.000279862,0.006514923,0.001335497,0.2185318,0.02344619,0.7403739],"study_design_scores_gemma":[0.0000214991,0.00006431915,0.004514637,0.004713899,0.0002578246,0.002397712,0.0002446067,0.005285016,0.0008630049,0.3860474,0.5954834,0.0001065834],"study_design_candidate":"not_applicable","study_design_consensus":null,"genre_codex":"review","genre_gemma":"review","genre_scores_codex":[0.0008234333,0.9591019,0.02922944,0.005344972,0.0003803562,0.00002754736,0.0002803359,0.0001060495,0.00470608],"genre_scores_gemma":[0.009336608,0.9780974,0.009297566,0.0009276875,0.0006182318,0.00006450054,0.0002857932,0.00002045134,0.001351845],"genre_candidate":"review","genre_consensus":"review","teacher_disagreement_score":0.004073785,"threshold_uncertainty_score":0.01656163,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.05186641628690011,"score_gpt":0.3296235514853078,"score_spread":0.2777571351984076,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}