{"id":"W2099332293","doi":"10.5966/sctm.2013-0019","title":"Overcoming Challenges to Initiating Cell Therapy Clinical Trials in Rapidly Developing Countries: India as a Model","year":2013,"lang":"en","type":"article","venue":"Stem Cells Translational Medicine","topic":"Biomedical Ethics and Regulation","field":"Medicine","cited_by":21,"is_retracted":false,"has_abstract":true,"ca_institutions":"Princess Margaret Cancer Centre; University Health Network","funders":"Indian Council of Medical Research","keywords":"Pace; Clinical trial; Translational research; Translational medicine; Stem cell; Biopharmaceutical; Medicine; Engineering ethics; Biotechnology; Engineering; Pathology; Biology","routes":{"ca_aff":true,"ca_fund":false,"ca_venue":false,"about_ca":false,"invisible_to_affiliation_only":false},"retraction":null,"screen":null,"direct_labels":[],"prediction":{"model_version":"codex-gemma-dda1882f352a","candidate_categories":[],"consensus_categories":[],"category_scores_codex":[0.00777488,0.0002599123,0.001104972,0.0003755835,0.00008605454,0.00001684135,0.0001219207,0.0004454119,0.0003924395],"category_scores_gemma":[0.0002142064,0.0001842762,0.0001541442,0.0003413594,0.0003611537,0.0001384006,0.0000168991,0.0005426091,0.00007476001],"about_ca_system_candidate":false,"about_ca_system_consensus":false,"about_ca_system_score_codex":0.00006370791,"about_ca_system_score_gemma":0.0007257868,"about_ca_topic_candidate":false,"about_ca_topic_consensus":false,"about_ca_topic_score_codex":0.00006681993,"about_ca_topic_score_gemma":0.00001458755,"domain_scores_codex":[0.9957116,0.0004987671,0.002022765,0.0004695114,0.0009483348,0.000348977],"domain_scores_gemma":[0.9959509,0.002867253,0.0003277918,0.0002125415,0.0002793018,0.0003621923],"domain_codex":null,"domain_gemma":null,"domain_candidate":null,"domain_consensus":null,"study_design_codex":"design_other","study_design_gemma":"observational","study_design_scores_codex":[0.002620598,0.001016879,0.006823169,0.002751724,0.0005726489,0.0001092151,0.05134618,0.001817493,0.04757603,0.06848937,0.001952941,0.8149238],"study_design_scores_gemma":[0.1225986,0.007991431,0.2709937,0.02310592,0.0008061716,0.0001434224,0.01207105,0.2535077,0.02394212,0.1348405,0.1457964,0.004203014],"study_design_candidate":"design_other","study_design_consensus":null,"genre_codex":"empirical","genre_gemma":"empirical","genre_scores_codex":[0.4805354,0.01713421,0.03904489,0.4389256,0.001611013,0.006299989,0.00002778702,0.0001856729,0.01623544],"genre_scores_gemma":[0.9755714,0.007848192,0.005901864,0.009592274,0.0007274931,0.00008914588,0.00003947864,0.00003868703,0.0001914863],"genre_candidate":"empirical","genre_consensus":"empirical","teacher_disagreement_score":0.8107207,"threshold_uncertainty_score":0.7514564,"prediction_status":"machine_predicted_unvalidated"},"machine_scores":{"provisional":true,"baseline":true,"maturity_gate_passed":false,"score_opus":0.2130750850688559,"score_gpt":0.4185432655159043,"score_spread":0.2054681804470485,"validation_status":"score_only:v0-immature-baseline","note":"Baseline scores from an immature model (maturity gate not passed). Scores rank; they never assert a category."}}